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DHBP Brand names, DHBP Analogs

DHBP Brand Names Mixture

  • No information avaliable

DHBP Chemical_Formula

C10H16NO+

DHBP RX_link

http://www.rxlist.com/cgi/generic3/edrophonium.htm

DHBP fda sheet

DHBP msds (material safety sheet)

DHBP MSDS

DHBP Synthesis Reference

No information avaliable

DHBP Molecular Weight

166.24 g/mol

DHBP Melting Point

No information avaliable

DHBP H2O Solubility

Appreciable as liquid hydrochloride salt

DHBP State

Liquid

DHBP LogP

-2.95

DHBP Dosage Forms

Liquid for injection

DHBP Indication

For the differential diagnosis of myasthenia gravis and as an adjunct in the evaluation of treatment requirements in this disease. It may also be used for evaluating emergency treatment in myasthenic crises.

DHBP Pharmacology

Edrophonium is a short and rapid-acting anticholinesterase drug. Its effect is manifest within 30 to 60 seconds after injection and lasts an average of 10 minutes. Edrophonium's pharmacologic action is due primarily to the inhibition or inactivation of acetylcholinesterase at sites of cholinergic transmission. Muscarinic receptors are found throughout the body, especially on muscle. Stimulation of these receptors causes to muscle contraction. In myasthenia gravis the body's immune system destroys many of the muscarinic receptors, so that the muscle becomes less responsive to nervous stimulation. Edrophonium chloride increases the amount of acetylcholine at the nerve endings. Increased levels of acetyl choline allow the remaining receptors to function more efficiently.

DHBP Absorption

Rapidly absorbed.

DHBP side effects and Toxicity

With drugs of this type, muscarine-like symptoms (nausea, vomiting, diarrhea, sweating, increased bronchial and salivary secretions and bradycardia) often appear with overdosage (cholinergic crisis).

DHBP Patient Information

No information avaliable

DHBP Organisms Affected

Humans and other mammals