Cyclocort
Brand names,
Cyclocort
Analogs
Cyclocort
Brand Names Mixture
Cyclocort
Chemical_Formula
C28H35FO7
Cyclocort
RX_link
http://www.rxlist.com/cgi/generic3/amcinonide.htm
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fda sheet
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msds (material safety sheet)
Cyclocort
Synthesis Reference
No information avaliable
Cyclocort
Molecular Weight
502.572 g/mol
Cyclocort
Melting Point
No information avaliable
Cyclocort
H2O Solubility
No information avaliable
Cyclocort
State
No information avaliable
Cyclocort
LogP
3.269
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Dosage Forms
Cream (0.1%); Lotion (0.1%); Ointment (0.1%)
Cyclocort
Indication
For the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.
Cyclocort
Pharmacology
Amcinonide is a topical corticosteroid. The topical corticosteroids constitute a class of primarily synthetic steroids used as anti-inflammatory and antipruritic agents. Amcinonide reduces or inhibits the actions of chemicals in the body that cause inflammation, redness, and swelling. The mechanism of anti-inflammatory activity of the topical corticosteroids is unclear. Various laboratory methods, including vasoconstrictor assays, are used to compare and predict potencies and/or clinical efficacies of the topical corticosteroids. There is some evidence to suggest that a recognizable correlation exists between vasoconstrictor potency and therapeutic efficacy in man. When in an ointment form, amcinonide also helps the skin maintain moisture.
Cyclocort
Absorption
Topical corticosteroids can be absorbed from normal intact skin. Inflammation and/or other disease processes in the skin increase percutaneous absorption.
Cyclocort
side effects and Toxicity
Results from acute toxicity studies do not indicate that any risk of acute intoxication is to be expected following a single dermal application of an overdose (application over a large area under conditions favorable to absorption) or inadvertent oral ingestion.
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Patient Information
Cyclocort
Organisms Affected
Humans and other mammals