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Coactin Brand names, Coactin Analogs

Coactin Brand Names Mixture

  • No information avaliable

Coactin Chemical_Formula


Coactin RX_link

No information avaliable

Coactin fda sheet

Coactin msds (material safety sheet)

Coactin MSDS

Coactin Synthesis Reference

No information avaliable

Coactin Molecular Weight

439.57 g/mol

Coactin Melting Point

156 oC

Coactin H2O Solubility


Coactin State


Coactin LogP


Coactin Dosage Forms


Coactin Indication

Used in the treatment of urinary tract infections caused by some strains of E. coli and klebsiella and enterobacter species.

Coactin Pharmacology

Amdinocillin is a novel, semisynthetic penicillin effective against many gram-negative bacteria. The antibacterial activity of amdinocillin is derived from its ability to bind specifically and avidly to Penicillin Binding Protein-2 (PBP 2). Amdinocillin is active alone against many gram-negative organisms. Pseudomonas and non-fermenting gram-negative bacteria, however, are usually resistant. Amdinocillin, in combination with many beta-lactams, exhibits marked synergy against many enterobacteriaceae. No such synergy can be demonstrated for gram-positive organisms or pseudomonas species. Amdinocillin is not beta-lactamase stable. Organisms which produce high levels of plasma-mediated beta-lactamase are resistant to the drug. Co-administration of probenecid results in markedly elevated plasma levels of amdinocillin and delays its excretion.

Coactin Absorption

Poorly absorbed if given orally.

Coactin side effects and Toxicity

No information avaliable

Coactin Patient Information

Coactin Organisms Affected

Gram-negative Bacteria