Citrulline
Brand names,
Citrulline
Analogs
Citrulline
Brand Names Mixture
Citrulline
Chemical_Formula
C6H13N3O3
Citrulline
RX_link
No information avaliable
Citrulline
fda sheet
Citrulline
msds (material safety sheet)
Citrulline
Synthesis Reference
No information avaliable
Citrulline
Molecular Weight
175.187 g/mol
Citrulline
Melting Point
214 oC
Citrulline
H2O Solubility
200 G/L (at 20 oC)
Citrulline
State
Solid
Citrulline
LogP
-4.034
Citrulline
Dosage Forms
Powder
Citrulline
Indication
Used for nutritional supplementation, also for treating dietary shortage or imbalance.
Citrulline
Pharmacology
A non-essential amino acid and a precursor of arginine. Citrulline supplements have been claimed to promote energy levels, stimulate the immune system and help detoxify ammonia (a cell toxin). L-citrulline is made from L-ornithine and carbamoyl phosphate in one of the central reactions in the urea cycle. It is also produced from L-arginine as a by-product of the reaction catalyzed by the enzyme NO synthase. L-citrulline, while being an amino acid, is not involved in protein synthesis and is not one of the amino acids coded for by DNA. Although citrulline cannot be incorporated in proteins during protein synthesis, several proteins are known to contain citrulline as an amino acid. These citrulline residues are generated by a family of enzymes called peptidylarginine deiminases (PADs), which convert the amino acid arginine into citrulline. Proteins that contain citrulline residues include myelin basic protein (MBP), fillagrin and several histone proteins.
Citrulline
Absorption
No information avaliable
Citrulline
side effects and Toxicity
No information avaliable
Citrulline
Patient Information
No information avaliable
Citrulline
Organisms Affected
Humans and other mammals