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Cinoxacin Brand names, Cinoxacin Analogs

Cinoxacin Brand Names Mixture

  • No information avaliable

Cinoxacin Chemical_Formula


Cinoxacin RX_link

Cinoxacin fda sheet

Cinoxacin FDA

Cinoxacin msds (material safety sheet)

Cinoxacin MSDS

Cinoxacin Synthesis Reference

No information avaliable

Cinoxacin Molecular Weight

262.218 g/mol

Cinoxacin Melting Point

261 oC

Cinoxacin H2O Solubility

No information avaliable

Cinoxacin State


Cinoxacin LogP


Cinoxacin Dosage Forms

Capsules (250mg and 500mg)

Cinoxacin Indication

For the treatment of initial and recurrent urinary tract infections in adults caused by the following susceptible microorganisms: Escherichia coli, Proteus mirabilis, Proteus vulgaris, Klebsiella species (including K. pneumoniae), and Enterobacter species.

Cinoxacin Pharmacology

Cinoxacin is a synthetic antibacterial agent with in vitro activity against many gram-negative aerobic bacteria, particularly strains of the Enterobacteriaceae family. Cinoxacin inhibits bacterial deoxyribonucleic acid (DNA) synthesis, is bactericidal, and is active over the entire urinary pH range. Cross resistance with nalidixic acid has been demonstrated.

Cinoxacin Absorption

Rapidly absorbed after oral administration. The presence of food delays absorption but does does not affect total absorption.

Cinoxacin side effects and Toxicity

Oral, subcutaneous, and intravenous LD50 in the rat is 3610 mg/kg, 1380 mg/kg, and 860 mg/kg, respectively. Oral, subcutaneous, and intravenous LD50 in the mouse is 2330 mg/kg, 900 mg/kg, and 850 mg/kg, respectively.Symptoms following an overdose of cinoxacin may include anorexia, nausea, vomiting, epigastric distress, and diarrhea. The severity of the epigastric distress and the diarrhea are dose related. Headache, dizziness, insomnia, photophobia, tinnitus, and a tingling sensation have been reported in some patients.

Cinoxacin Patient Information

Cinoxacin Organisms Affected

Enteric bacteria and other eubacteria