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Brand names,
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Analogs
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Brand Names Mixture
- Marvelon 21 Tab (Desogestrel + Ethinyl Estradiol)
- Marvelon 28 Tab (Desogestrel + Ethinyl Estradiol)
- Ortho-Cept Tablets (21 Day) (Desogestrel + Ethinyl Estradiol)
- Ortho-Cept Tablets (28 Day) (Desogestrel + Ethinyl Estradiol)
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Chemical_Formula
C22H30O
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RX_link
http://www.rxlist.com/cgi/generic/desest.htm
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fda sheet
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msds (material safety sheet)
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Synthesis Reference
Hu QY, et al. J Am Chem Soc. 2004 May 19;126(19):5984-6.
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Molecular Weight
310.473 g/mol
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Melting Point
109.5 oC
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H2O Solubility
No information avaliable
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State
Solid
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LogP
3.718
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Dosage Forms
Tablet
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Indication
For the prevention of pregnancy in women who elect to use this product as a method of contraception.
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Pharmacology
Desogestrel is used as a female contraceptive. Desogestrel is a progestin or a synthetic form of the naturally occurring female sex hormone, progesterone. In a woman's normal menstrual cycle, an egg matures and is released from the ovaries (ovulation). The ovary then produces progesterone, preventing the release of further eggs and priming the lining of the womb for a possible pregnancy. If pregnancy occurs, progesterone levels in the body remain high, maintaining the womb lining. If pregnancy does not occur, progesterone levels in the body fall, resulting in a menstrual period. Desogestrel tricks the body processes into thinking that ovulation has already occurred, by maintaining high levels of the synthetic progesterone. This prevents the release of eggs from the ovaries.
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Absorption
Following oral administration, the relative bioavailability of desogestrel compared to a solution, as measured by serum levels of etonogestrel, is approximately 100%.
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side effects and Toxicity
Symptoms of overdose include nausea and vaginal bleeding.
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Patient Information
No information avaliable
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Organisms Affected
Humans and other mammals