Ceclor CD
Brand names,
Ceclor CD
Analogs
Ceclor CD
Brand Names Mixture
Ceclor CD
Chemical_Formula
C15H14ClN3O4S
Ceclor CD
RX_link
http://www.rxlist.com/cgi/generic/cefaclor.htm
Ceclor CD
fda sheet
Ceclor CD
msds (material safety sheet)
Ceclor CD
Synthesis Reference
R. R. Chauvette, U.S. Pat. 3,925,372 (1975)
Ceclor CD
Molecular Weight
367.808 g/mol
Ceclor CD
Melting Point
327 oC
Ceclor CD
H2O Solubility
8.6 mg/mL
Ceclor CD
State
Solid
Ceclor CD
LogP
0.517
Ceclor CD
Dosage Forms
Capsule; Powder; Powder for solution; Powder for suspension; Suspension
Ceclor CD
Indication
For the treatment of certain infections caused by bacteria such as pneumonia and ear, lung, skin, throat, and urinary tract infections.
Ceclor CD
Pharmacology
Cefaclor is a second generation cephalosporin antibiotic with a spectrum resembling first-generation cephalosporins. In vitro tests demonstrate that the bactericidal action of the cephalosporins results from inhibition of cell-wall synthesis. Cefaclor has been shown to be active against most strains of the following microorganisms, both in vitro and in clinical infections: Gram positive aerobes - Staphylococci (including coagulase-positive, coagulase-negative, and penicillinase-producing strains), Streptococcus pneumoniae, and Streptococcus pyogenes (group A ß-hemolytic streptococci). Gram-negative aerobes - Escherichia coli, Haemophilus influenzae (including ß-lactamase-producing ampicillin-resistant strains), Klebsiella sp, and Proteus mirabilis.
Ceclor CD
Absorption
Well absorbed after oral administration, independent of food intake.
Ceclor CD
side effects and Toxicity
Symptoms of overdose include diarrhea, nausea, stomach upset, and vomiting.
Ceclor CD
Patient Information
Patients should be counseled that antibacterial drugs including Ceclor should only be used to treat bacterial
infections. They do not treat viral infections (e.g., the common cold). When Ceclor is prescribed to treat a
bacterial infection, patients should be told that although it is common to feel better early in the course of
therapy, the medication should be taken exactly as directed. Skipping doses or not completing the full course of
therapy may (1) decrease the effectiveness of the immediate treatment and (2) increase the likelihood that bacteria
will develop resistance and will not be treatable by Ceclor or other antibacterial drugs in the future.
Ceclor CD
Organisms Affected
Enteric bacteria and other eubacteria