Butalbital
Brand names,
Butalbital
Analogs
Butalbital
Brand Names Mixture
- Fiorinal C1/2 Cap (Acetylsalicylic Acid + Butalbital + Caffeine + Codeine Phosphate)
- Fiorinal C1/4 Cap (Acetylsalicylic Acid + Butalbital + Caffeine + Codeine Phosphate)
- Fiorinal Tab (Acetylsalicylic Acid + Butalbital + Caffeine)
- Ratio-Tecnal (Acetylsalicylic Acid + Butalbital + Caffeine)
- Ratio-Tecnal C 1/2 (Acetylsalicylic Acid + Butalbital + Caffeine + Codeine Phosphate)
- Ratio-Tecnal C1/4 (Acetylsalicylic Acid + Butalbital + Caffeine + Codeine Phosphate)
- Trianal Capsules (Acetylsalicylic Acid + Butalbital + Caffeine)
- Trianal Tablet (Acetylsalicylic Acid + Butalbital + Caffeine)
- Trianal-C 1/2 Capsule (Acetylsalicylic Acid + Butalbital + Caffeine + Codeine Phosphate)
Butalbital
Chemical_Formula
C11H16N2O3
Butalbital
RX_link
http://www.rxlist.com/cgi/generic/esgic.htm
Butalbital
fda sheet
Butalbital
msds (material safety sheet)
Butalbital
Synthesis Reference
J. Am. Chem. Soc. 47, 2236 (1925)
Butalbital
Molecular Weight
224.256 g/mol
Butalbital
Melting Point
138-139 oC
Butalbital
H2O Solubility
1700 mg/L
Butalbital
State
Solid
Butalbital
LogP
1.429
Butalbital
Dosage Forms
Tablet
Butalbital
Indication
Used in combination with acetaminophen or aspirin and caffeine for its sedative and relaxant effects in the treatment of tension headaches, migraines, and pain.
Butalbital
Pharmacology
Butalbital is a short to intermediate-acting barbiturate. Barbiturates act as nonselective depressants of the central nervous system (CNS), capable of producing all levels of CNS mood alteration from excitation to mild sedation, hypnosis, and deep coma. In sufficiently high therapeutic doses, barbiturates induce anesthesia.
Butalbital
Absorption
Well absorbed from the gastrointestinal tract and is expected to distribute to most tissues in the body.
Butalbital
side effects and Toxicity
Symptoms of acute barbiturate poisoning include drowsiness, confusion, coma, respiratory depression, hypotension, and shock.
Butalbital
Patient Information
PATIENT INFORMATION
This product may impair mental and/or physical abilities required for the performance of potentially hazardous tasks such as driving a car or operating machinery. Such tasks should be avoided while taking this product.
Alcohol and other CNS depressants may produce an additive CNS depression, when taken with this combination product, and should be avoided.
Butalbital may be habit-forming. Patients should take the drug only for as long as it is prescribed, in the amounts prescribed, and no more frequently than prescribed.
Butalbital
Organisms Affected
Humans and other mammals