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Brevital sodium Brand names, Brevital sodium Analogs

Brevital sodium Brand Names Mixture

  • No information avaliable

Brevital sodium Chemical_Formula


Brevital sodium RX_link

Brevital sodium fda sheet

Brevital_sodium FDA

Brevital sodium msds (material safety sheet)

Brevital sodium Synthesis Reference

No information avaliable

Brevital sodium Molecular Weight

262.304 g/mol

Brevital sodium Melting Point

No information avaliable

Brevital sodium H2O Solubility

No information avaliable

Brevital sodium State


Brevital sodium LogP


Brevital sodium Dosage Forms

Powder for solution

Brevital sodium Indication

Indicated for use as an intravenous anaesthetic.

Brevital sodium Pharmacology

Methohexital, a barbiturate, is used for the induction of anesthesia prior to the use of other general anesthetic agents and for induction of anesthesia for short surgical, diagnostic, or therapeutic procedures associated with minimal painful stimuli. Little analgesia is conferred by barbiturates; their use in the presence of pain may result in excitation.

Brevital sodium Absorption

The absolute bioavailability following rectal administration of methohexital is 17%.

Brevital sodium side effects and Toxicity

The onset of toxicity following an overdose of intravenously administered methohexital will be within seconds of the infusion. If methohexital is administered rectally or is ingested, the onset of toxicity may be delayed. The manifestations of an ultrashort-acting barbiturate in overdose include central nervous system depression, respiratory depression, hypotension, loss of peripheral vascular resistance, and muscular hyperactivity ranging from twitching to convulsive-like movements. Other findings may include convulsions and allergic reactions. Following massive exposure to any barbiturate, pulmonary edema, circulatory collapse with loss of peripheral vascular tone, and cardiac arrest may occur.

Brevital sodium Patient Information

When appropriate, patients should be instructed as to the hazards of drowsiness that may follow use of barbiturates. Outpatients should be released in the company of another individual, and no skilled activities, such as operating machinery or driving a motor vehicle, should be engaged in for 8 to 12 hours.

Brevital sodium Organisms Affected

Humans and other mammals