Bimatoprost
Bimatoprost Brand names, Bimatoprost Analogs
Bimatoprost Brand Names Mixture
- No information avaliable
Bimatoprost Chemical_Formula
C25H37NO4
Bimatoprost RX_link
http://www.rxlist.com/cgi/generic2/bimatoprost.htm
Bimatoprost fda sheet
Bimatoprost msds (material safety sheet)
Bimatoprost Synthesis Reference
No information avaliable
Bimatoprost Molecular Weight
415.566 g/mol
Bimatoprost Melting Point
No information avaliable
Bimatoprost H2O Solubility
Slightly soluble
Bimatoprost State
Solid
Bimatoprost LogP
2.436
Bimatoprost Dosage Forms
Ophthalmic solution (0.03%)
Bimatoprost Indication
For the reduction of elevated intraocular pressure in patients with open angle glaucoma or ocular hypertension who are intolerant of other intraocular pressure lowering medications or insufficiently responsive (failed to achieve target IOP determined after multiple measurements over time) to another intraocular pressure lowering medication.
Bimatoprost Pharmacology
Bimatoprost is a prostamide, a synthetic structural analog of prostaglandin with ocular hypotensive activity. It selectively mimics the effects of naturally occurring substances, prostamides. Bimatoprost lowers intraocular pressure (IOP) in humans. Elevated IOP presents a major risk factor for glaucomatous field loss. The higher the level of IOP, the greater the likelihood of optic nerve damage and visual field loss.
Bimatoprost Absorption
Systemically absorbed when administered to the eye.
Bimatoprost side effects and Toxicity
In oral (by gavage) mouse and rat studies, doses up to 100 mg/kg/day did not produce any toxicity. This dose expressed as mg/m2 is at least 70 times higher than the accidental dose of one bottle of bimatoprost for a 10 kg child.
Bimatoprost Patient Information
Bimatoprost Organisms Affected
Humans and other mammals
