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Argatroban Brand names, Argatroban Analogs

Argatroban Brand Names Mixture

  • No information avaliable

Argatroban Chemical_Formula


Argatroban RX_link

Argatroban fda sheet

Argatroban FDA

Argatroban msds (material safety sheet)

Argatroban Synthesis Reference

No information avaliable

Argatroban Molecular Weight

508.635 g/mol

Argatroban Melting Point

No information avaliable

Argatroban H2O Solubility

No information avaliable

Argatroban State


Argatroban LogP


Argatroban Dosage Forms


Argatroban Indication

For prophylaxis or treatment of thrombosis in patients with heparin-induced thrombocytopenia

Argatroban Pharmacology

Argatroban is a synthetic direct thrombin inhibitor derived from L-arginine indicated as an anticoagulant for prophylaxis or treatment of thrombosis in patients with heparin-induced thrombocytopenia. Argatroban is a direct thrombin inhibitor that reversibly binds to the thrombin active site. Argatroban does not require the co-factor antithrombin III for antithrombotic activity. Argatroban exerts its anticoagulant effects by inhibiting thrombin-catalyzed or -induced reactions, including fibrin formation; activation of coagulation factors V, VIII, and XIII; protein C; and platelet aggregation. Argatroban is highly selective for thrombin with an inhibitory constant (Ki) of 0.04 µM. At therapeutic concentrations, Argatroban has little or no effect on related serine proteases (trypsin, factor Xa, plasmin, and kallikrein).

Argatroban Absorption

No information avaliable

Argatroban side effects and Toxicity

No information avaliable

Argatroban Patient Information

No information avaliable

Argatroban Organisms Affected

Humans and other mammals