Antilepsin
Brand names,
Antilepsin
Analogs
Antilepsin
Brand Names Mixture
Antilepsin
Chemical_Formula
C15H10ClN3O3
Antilepsin
RX_link
http://www.rxlist.com/cgi/generic/clonaz.htm
Antilepsin
fda sheet
Antilepsin
msds (material safety sheet)
Antilepsin
Synthesis Reference
L. H. Sternbach et al.; J. Med. Chem. 6,261 (1963)
Antilepsin
Molecular Weight
315.711 g/mol
Antilepsin
Melting Point
236.5 - 238.5 oC
Antilepsin
H2O Solubility
<0.1 mg/mL
Antilepsin
State
Solid
Antilepsin
LogP
2.722
Antilepsin
Dosage Forms
Tablet
Antilepsin
Indication
Used as an anticonvulsant in the treatment of the Lennox-Gastaut syndrome (petit mal variant), akinetic and myoclonic seizures.
Antilepsin
Pharmacology
Clonazepam, a benzodiazepine, is used primarily as an anticonvulsant in the treatment of absence seizures, petit mal variant seizures (Lennox-Gastaut syndrome), akinetic and myoclonic seizures, and nocturnal myoclonus.
Antilepsin
Absorption
Clonazepam is rapidly and completely absorbed after oral administration. The absolute bioavailability of clonazepam is about 90%.
Antilepsin
side effects and Toxicity
Somnolence, confusion, coma, and diminished reflexes
Antilepsin
Patient Information
Clonazepam is used for the treatment of seizures. Notify your physician if you
are pregnant or nursing. This medication may cause dizziness, drowsiness, or
blurred vision; use caution while driving or operating hazardous machinery.
Do not take any other sedating drugs or drink alcohol while taking clonazepam.
Do not change the dose or stop taking clonazepam without talking with your physician.
This medication may be habit forming. Seizures or withdrawal symptoms may occur after
you stop taking it. This medication should be taken with meals to avoid stomach upset.
Antilepsin
Organisms Affected
Humans and other mammals