Anisindione
Brand names,
Anisindione
Analogs
Anisindione
Brand Names Mixture
Anisindione
Chemical_Formula
C16H12O3
Anisindione
RX_link
http://www.rxlist.com/cgi/generic/miradon.htm
Anisindione
fda sheet
Anisindione
msds (material safety sheet)
Anisindione
Synthesis Reference
No information avaliable
Anisindione
Molecular Weight
252.265 g/mol
Anisindione
Melting Point
156.5 oC
Anisindione
H2O Solubility
79.8 mg/L
Anisindione
State
Solid
Anisindione
LogP
2.472
Anisindione
Dosage Forms
Tablet (oral, 50mg)
Anisindione
Indication
For the prophylaxis and treatment of venous thrombosis and its extension, the treatment of atrial fibrillation with embolization, the prophylaxis and treatment of pulmonary embolism, and as an adjunct in the treatment of coronary occlusion.
Anisindione
Pharmacology
Anisindione is a synthetic anticoagulant and an indanedione derivative. It is prescribed only if you cannot take coumarin-type anticoagulants such as coumadin as anisindione is a powerful drug with serious potential side effects. Anticoagulants decrease the clotting ability of the blood and therefore help to prevent harmful clots from forming in the blood vessels. These medicines are sometimes called blood thinners, although they do not actually thin the blood. They also will not dissolve clots that already have formed, but they may prevent the clots from becoming larger and causing more serious problems.
Anisindione
Absorption
Accumulation does not occur with repeated dosing.
Anisindione
side effects and Toxicity
An overdose is likely to cause abnormal bleeding, for which the symptoms include: bleeding from gums or nose, blood in urine or stools, excessive bleeding from minor cuts, patches of discoloration or bruises on the skin.
Anisindione
Patient Information
Anisindione
Organisms Affected
Humans and other mammals