Anidulafungin
Anidulafungin Brand names, Anidulafungin Analogs
Anidulafungin Brand Names Mixture
- No information avaliable
Anidulafungin Chemical_Formula
C58H73N7O17
Anidulafungin RX_link
No information avaliable
Anidulafungin fda sheet
Anidulafungin msds (material safety sheet)
Anidulafungin Synthesis Reference
No information avaliable
Anidulafungin Molecular Weight
1140.24 g/mol
Anidulafungin Melting Point
No information avaliable
Anidulafungin H2O Solubility
Practically insoluble
Anidulafungin State
Solid
Anidulafungin LogP
0.216
Anidulafungin Dosage Forms
Injection (50 mg vials to be reconstituted prior to injection)
Anidulafungin Indication
For use in the treatment of the following fungal infections: Candidemia and other forms of Candida infections (intra-abdominal abscess, and peritonitis) and esophageal candidiasis.
Anidulafungin Pharmacology
Anidulafungin is a semi-synthetic lipopeptide synthesized from a fermentation product of Aspergillus nidulans. Anidulafungin is an echinocandin, a class of antifungal drugs that inhibits the synthesis of 1,3-β-D-glucan, an essential component of fungal cell walls. Anidulafungin is active in vitro against Candida albicans, C. glabrata, C. parapsilosis, and C. tropicalis.
Anidulafungin Absorption
No information avaliable
Anidulafungin side effects and Toxicity
During clinical trials a single 400 mg dose of anidulafungin was inadvertently administered as a loading dose. No clinical adverse events were reported. The maximum non-lethal dose of anidulafungin in rats was 50 mg/kg, a dose which is equivalent to 10 times the recommended daily dose for esophageal candidiasis (50mg/day).
Anidulafungin Patient Information
Anidulafungin Organisms Affected
Aspergillis, Candida and other fungi
