Alferon (Interferon Sciences Inc.)
Alferon (Interferon Sciences Inc.) Brand names, Alferon (Interferon Sciences Inc.) Analogs
Alferon (Interferon Sciences Inc.) Brand Names Mixture
- No information avaliable
Alferon (Interferon Sciences Inc.) Chemical_Formula
C860H1353N227O255S9
Alferon (Interferon Sciences Inc.) RX_link
No information avaliable
Alferon (Interferon Sciences Inc.) fda sheet
Alferon (Interferon Sciences Inc.) msds (material safety sheet)
Alferon (Interferon Sciences Inc.) Synthesis Reference
No information avaliable
Alferon (Interferon Sciences Inc.) Molecular Weight
19241.1
Alferon (Interferon Sciences Inc.) Melting Point
61 oC (Beldarrain, A. et al., Biochemistry 38:7865-7873 (1999)) Davis JM, Narachi MA, Levine HL, Alton NK, Arakawa T. Conformation and stability of two recombinant human interferon-alpha analogs.
Alferon (Interferon Sciences Inc.) H2O Solubility
No information avaliable
Alferon (Interferon Sciences Inc.) State
Liquid
Alferon (Interferon Sciences Inc.) LogP
-0.336
Alferon (Interferon Sciences Inc.) Dosage Forms
Solution (injection)
Alferon (Interferon Sciences Inc.) Indication
For the treatment of hairy cell leukemia, malignant melanoma, AIDS-related Kaposi's sarcoma, refractory or recurring external condylomata acuminata in patients 18 years of age or older, laryngeal papillomatosis in children and some types of hepatitis
Alferon (Interferon Sciences Inc.) Pharmacology
Interferon alfa-n3 upregulates the expression of MHC I proteins, allowing for increased presentation of peptides derived from viral antigens. This enhances the activation of CD8+ T cells that are the precursors for cytotoxic T lymphocytes (CTLs) and makes the macrophage a better target for CTL-mediated killing. Interferon alpha also induce the synthesis of several key antiviral mediators, including 2'-5' oligoadenylate synthetase (2'-5' A synthetase), beta-2 microglobulin, neopterin and protein kinase R.
Alferon (Interferon Sciences Inc.) Absorption
No information avaliable
Alferon (Interferon Sciences Inc.) side effects and Toxicity
No information avaliable
Alferon (Interferon Sciences Inc.) Patient Information
No information avaliable
Alferon (Interferon Sciences Inc.) Organisms Affected
No information avaliable
