Alefacept
Brand names,
Alefacept
Analogs
Alefacept
Brand Names Mixture
Alefacept
Chemical_Formula
C2306H3594N610O694S26
Alefacept
RX_link
http://www.rxlist.com/cgi/generic3/amevive.htm
Alefacept
fda sheet
Alefacept
msds (material safety sheet)
Alefacept
Synthesis Reference
No information avaliable
Alefacept
Molecular Weight
51801.1
Alefacept
Melting Point
No information avaliable
Alefacept
H2O Solubility
No information avaliable
Alefacept
State
Liquid
Alefacept
LogP
-0.432
Alefacept
Dosage Forms
Powder for solution
Alefacept
Indication
For treatment of moderate to severe chronic plaque psoriasis
Alefacept
Pharmacology
Interferes with lymphocyte activation by specifically binding to the lymphocyte antigen, CD2, and inhibiting LFA-3/CD2 interaction. Activation of T lymphocytes involving the interaction between LFA-3 on antigen-presenting cells and CD2 on T lymphocytes plays a role in the pathophysiology of chronic plaque psoriasis. Also causes a reduction in subsets of CD2+ T lymphocytes as well as CD4+ and CD8+ T lymphocytes.
Alefacept
Absorption
No information avaliable
Alefacept
side effects and Toxicity
No information avaliable
Alefacept
Patient Information
BIOD00055.html
Alefacept
Organisms Affected
Humans and other mammals