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Brand names,
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Analogs
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Brand Names Mixture
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Chemical_Formula
No information avaliable
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RX_link
http://www.rxlist.com/cgi/generic3/extraneal.htm
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fda sheet
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msds (material safety sheet)
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Synthesis Reference
No information avaliable
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Molecular Weight
13000-19000 g/mol
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Melting Point
No information avaliable
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H2O Solubility
80 mg/mL
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State
Solid
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LogP
No information avaliable
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Dosage Forms
Solution (for injection)
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Indication
Used for continuous ambulatory peritoneal dialysis (CAPD) of diabetic patients or automated peritoneal dialysis (APD) for the management of end-stage renal disease.
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Pharmacology
Icodextrin is an iso-osmotic peritoneal dialysis solution containing glucose polymers. It is used primarily for ambulatory peritoneal dialysis (CAPD) of diabetic patients and automated peritoneal dialysis (APD) for patients with end-stage renal disease. It is injected as a solution into the peritoneal cavity. The drug is absorbed via convective transport via peritoneal lymphatic pathways.
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Absorption
40% of instilled icodextrin was absorbed from the peritoneal solution during a 12-hour dwell.
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side effects and Toxicity
No information avaliable
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Patient Information
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Organisms Affected
Humans and other mammals