3-Carboxy-2-hydroxy-N,N,N-trimethyl-1-propanaminium
Brand names,
3-Carboxy-2-hydroxy-N,N,N-trimethyl-1-propanaminium
Analogs
3-Carboxy-2-hydroxy-N,N,N-trimethyl-1-propanaminium
Brand Names Mixture
3-Carboxy-2-hydroxy-N,N,N-trimethyl-1-propanaminium
Chemical_Formula
C16H16ClN3O4
3-Carboxy-2-hydroxy-N,N,N-trimethyl-1-propanaminium
RX_link
http://www.rxlist.com/cgi/generic/loracarb.htm
3-Carboxy-2-hydroxy-N,N,N-trimethyl-1-propanaminium
fda sheet
3-Carboxy-2-hydroxy-N,N,N-trimethyl-1-propanaminium
msds (material safety sheet)
3-Carboxy-2-hydroxy-N,N,N-trimethyl-1-propanaminium
Synthesis Reference
No information avaliable
3-Carboxy-2-hydroxy-N,N,N-trimethyl-1-propanaminium
Molecular Weight
349.769 g/mol
3-Carboxy-2-hydroxy-N,N,N-trimethyl-1-propanaminium
Melting Point
No information avaliable
3-Carboxy-2-hydroxy-N,N,N-trimethyl-1-propanaminium
H2O Solubility
No information avaliable
3-Carboxy-2-hydroxy-N,N,N-trimethyl-1-propanaminium
State
Solid
3-Carboxy-2-hydroxy-N,N,N-trimethyl-1-propanaminium
LogP
0.286
3-Carboxy-2-hydroxy-N,N,N-trimethyl-1-propanaminium
Dosage Forms
No information avaliable
3-Carboxy-2-hydroxy-N,N,N-trimethyl-1-propanaminium
Indication
Used to treat upper respiratory tract bacterial infections, chronic bronchitis, pneumonia, sinusitis, pharyntitis and tonsillitis, skin absceses, urinary tract infections and pyelonephritis caused by E. coli, S. pyogenes, S. aureus, S. saprphyticus, S. penumoniae, H. influenzae and M. catarrhalis.
3-Carboxy-2-hydroxy-N,N,N-trimethyl-1-propanaminium
Pharmacology
Loracarbef is considered a second generation cephalosporin antibiotic. The advantages of cephalosporin antibiotics include a broad range of activity, a safe record in children with almost no dose-related toxicity, and the lack of need to monitor levels. Adverse reactions are rare and consist primarily of hypersensitivity reactions with urticaria, nonspecific rash, and pruritus. Loracarbef can be used to treat a large number of bacterial infections caused by gram-negative and gram-positive bacteria, including upper respiratory tract bacterial infections, chronic bronchitis, pneumonia, sinusitis, pharyntitis and tonsillitis, skin absceses, urinary tract infections and pyelonephritis caused by E. coli, S. pyogenes, S. aureus, S. saprphyticus, S. penumoniae, H. influenzae and M. catarrhalis.
3-Carboxy-2-hydroxy-N,N,N-trimethyl-1-propanaminium
Absorption
Well absorbed with approximately 90% absorbed from the gastrointestinal tract after oral ingestion.
3-Carboxy-2-hydroxy-N,N,N-trimethyl-1-propanaminium
side effects and Toxicity
Adverse effects include diarrhea, nausea, stomach upset, vomiting, headache, dizziness, rash, bone marrow depression.
3-Carboxy-2-hydroxy-N,N,N-trimethyl-1-propanaminium
Patient Information
http://www.drugs.com/MTM/lomefloxacin.html
3-Carboxy-2-hydroxy-N,N,N-trimethyl-1-propanaminium
Organisms Affected
Many kinds of gram-negative and gram-positive eubacteria