2-Amino-3-(p-hydroxyphenyl)propionic acid
Brand names,
2-Amino-3-(p-hydroxyphenyl)propionic acid
Analogs
2-Amino-3-(p-hydroxyphenyl)propionic acid
Brand Names Mixture
- Tyrosine, L-
- (-)-a-Amino-p-hydroxyhydrocinnamic acid
- (S)-a-Amino-4-hydroxybenzenepropanoic acid
- (S)-Tyrosine
- Benzenepropanoic acid, a-amino-4-hydroxy-, (S)-
- L-Phenylalanine, 4-hydroxy-
- L-p-Tyrosine
- L-tyrosine
- Propanoic acid, 2-amino-3-(4-hydroxyphenyl)-, (S)-
- Tyrosine
- p-Tyrosine
2-Amino-3-(p-hydroxyphenyl)propionic acid
Chemical_Formula
C9H11N1O3
2-Amino-3-(p-hydroxyphenyl)propionic acid
RX_link
No information avaliable
2-Amino-3-(p-hydroxyphenyl)propionic acid
fda sheet
2-Amino-3-(p-hydroxyphenyl)propionic acid
msds (material safety sheet)
2-Amino-3-(p-hydroxyphenyl)propionic acid
Synthesis Reference
No information avaliable
2-Amino-3-(p-hydroxyphenyl)propionic acid
Molecular Weight
181.191 g/mol
2-Amino-3-(p-hydroxyphenyl)propionic acid
Melting Point
342-344 oC
2-Amino-3-(p-hydroxyphenyl)propionic acid
H2O Solubility
Slightly soluble
2-Amino-3-(p-hydroxyphenyl)propionic acid
State
Solid
2-Amino-3-(p-hydroxyphenyl)propionic acid
LogP
-1.87
2-Amino-3-(p-hydroxyphenyl)propionic acid
Dosage Forms
Capsules (300 and 500 mg), Powder, and Tablets (300, 500, and 1000 mg)
2-Amino-3-(p-hydroxyphenyl)propionic acid
Indication
Tyrosine is claimed to act as an effective antidepressant, however results are mixed. Tyrosine has also been claimed to reduce stress and combat narcolepsy and chronic fatigue, however these claims have been refuted by some studies.
2-Amino-3-(p-hydroxyphenyl)propionic acid
Pharmacology
Tyrosine is a nonessential amino acid synthesized in the body from phenylalanine. Tyrosine is critical for the production of the body's proteins, enzymes and muscle tissue. Tyrosine is a precursor to the neurotransmitters norepinephrine and dopamine. It can act as a mood elevator and an anti-depressant. It may improve memory and increase mental alertness. Tyrosine aids in the production of melanin and plays a critical role in the production of thyroxin (thyroid hormones). Tyrosine deficiencies are manifested by hypothyroidism, low blood pressure and low body temperature. Supplemental tyrosine has been used to reduce stress and combat narcolepsy and chronic fatigue.
2-Amino-3-(p-hydroxyphenyl)propionic acid
Absorption
L-tyrosine is absorbed from the small intestine by a sodium-dependent active transport process.
2-Amino-3-(p-hydroxyphenyl)propionic acid
side effects and Toxicity
L-Tyrosine has very low toxicity. There have been very few reports of toxicity. LD50 (oral, rat) > 5110 mg/kg.
2-Amino-3-(p-hydroxyphenyl)propionic acid
Patient Information
Pregnant women and nursing mothers should avoid supplementation with L-tyrosine.
2-Amino-3-(p-hydroxyphenyl)propionic acid
Organisms Affected
Humans and other mammals