1,2-Dithiolane-3R-pentanoic acid
1,2-Dithiolane-3R-pentanoic acid Brand names, 1,2-Dithiolane-3R-pentanoic acid Analogs
1,2-Dithiolane-3R-pentanoic acid Brand Names Mixture
- No information avaliable
1,2-Dithiolane-3R-pentanoic acid Chemical_Formula
C8H14O2S2
1,2-Dithiolane-3R-pentanoic acid RX_link
No information avaliable
1,2-Dithiolane-3R-pentanoic acid fda sheet
1,2-Dithiolane-3R-pentanoic acid msds (material safety sheet)
1,2-Dithiolane-3R-pentanoic acid Synthesis Reference
No information avaliable
1,2-Dithiolane-3R-pentanoic acid Molecular Weight
206.317 g/mol
1,2-Dithiolane-3R-pentanoic acid Melting Point
No information avaliable
1,2-Dithiolane-3R-pentanoic acid H2O Solubility
Insoluble
1,2-Dithiolane-3R-pentanoic acid State
Solid
1,2-Dithiolane-3R-pentanoic acid LogP
1.89
1,2-Dithiolane-3R-pentanoic acid Dosage Forms
No information avaliable
1,2-Dithiolane-3R-pentanoic acid Indication
For nutritional supplementation, also for treating dietary shortage or imbalance.
1,2-Dithiolane-3R-pentanoic acid Pharmacology
Lipoic acid (or α-lipoic acid) is able to pass the blood-brain barrier and is putatively used for detoxification of mercury attached to the brain cells. It can mobilise bound mercury into the blood stream as it is a mercaptan (sulfur compound which readily binds to the mercury). In the blood stream, another chelator such as dimercaptosuccinic acid (DMSA) or methylsulfonylmethane (MSM) is used to transfer mercury safely into the urine for excretion. Neither DMSA nor MSM can cross the blood-brain barrier, which is why both lipoic acid and DMSA are used. It is hypothesized that this treatment-along with carnitine, dimethylglycine (DMG), Vitamin B6, folic acid, and magnesium—could be used to treat autism and amalgam poisoning. In this hypothesis, the reason why autism is difficult to treat is that mercury is attached to the brain cells and most medicines and vitamin supplements do not penetrate the blood-brain barrier. However, α-lipoic acid and perhaps vitamin B12 could making it possible for other chelators to remove mercury safely out of the body and could perhaps one day be used as a treatment for autism. Because lipoic acid is related to cellular uptake of glucose and it is both soluble in water and fat, it is being used for treatment in diabetes. It may be helpful for people with Alzheimer's disease or Parkinson's disease.
1,2-Dithiolane-3R-pentanoic acid Absorption
No information avaliable
1,2-Dithiolane-3R-pentanoic acid side effects and Toxicity
No information avaliable
1,2-Dithiolane-3R-pentanoic acid Patient Information
No information avaliable
1,2-Dithiolane-3R-pentanoic acid Organisms Affected
Humans and other mammals
