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Lopril Nombres de marca, Lopril Analogos

Lopril Marca los nombres de mezcla

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  • Lopril Formula quimica

    C9H15NO3S

    Lopril RX enlace

    http://www.rxlist.com/cgi/generic/captop.htm

    Lopril FDA hoja

    Lopril MSDS (hoja de seguridad de materiales)

    Lopril MSDS

    Lopril Sintesis de referencia

    DW Cushman, EE.UU. Pat. 4,046,889 (1977)

    Lopril Peso molecular

    217.286 g/mol

    Lopril Punto de fusion

    106oC

    Lopril H2O Solubilidad

    Muy soluble

    Lopril Estado

    Solid

    Lopril LogP

    0.546

    Lopril Formas de dosificacion

    Tablet (12,5 mg, 25 mg, 50 mg o 100 mg)

    Lopril Indicacion

    Para el tratamiento de la hipertensión. Se puede utilizar solo o en combinación con diuréticos tiazídicos.

    Lopril Farmacologia

    Captopril, un inhibidor de la enzima convertidora de angiotensina (ECA), se utiliza para tratar la hipertensión, insuficiencia cardiaca congestiva, y síndromes renales como la nefropatía diabética y la esclerodermia. El efecto adverso y las limitaciones farmacocinéticas del captopril estimulado el desarrollo de inhibidores de la ECA enalapril y posteriores.

    Lopril Absorcion

    75% sin alimentos (la presencia de alimentos en el tracto gastrointestinal reduce la absorción de unos 30 a 40 por ciento).

    Lopril Toxicidad

    Los síntomas de sobredosis incluyen coma, letargo, baja presión arterial, la lentitud, y el estómago e irritación intestinal y la hiperactividad.

    Lopril Informacion de Pacientes

    Patients should be advised to immediately report to their physician any signs or symptoms suggesting angioedema (e.g., swelling of face, eyes, lips, tongue, larynx and extremities; difficulty in swallowing or breathing; hoarseness) and to discontinue therapy.

    Patients should be told to report promptly any indication of infection (e.g., sore throat, fever),which may be a sign of neutropenia, or of progressive edema which might be related to proteinuria and nephrotic syndrome.

    All patients should be cautioned that excessive perspiration and dehydration may lead to an excessive fall in blood pressure because of reduction in fluid volume. Other causes of volume depletion such as vomiting or diarrhea may also lead to a fall in blood pressure; patients should be advised to consult with the physician.

    Patients should be advised not to use potassium-sparing diuret-ics, potassium supplements or potassium-containing salt substitutes without consulting their physician.

    Patients should be warned against interruption or discontinuation of medication unless instructed by the physician.

    Heart failure patients on captopril therapy should be cautioned against rapid increases in physical activity.

    Patients should be informed that captopril should be taken one hour before meals.

    Lopril Organismos afectados

    Humanos y otros mamíferos