Trastuzumab
Trastuzumab Brand names, Trastuzumab Analogs
Trastuzumab Brand Names Mixture
- Filaribits Plus 180/136mg Chewable Tablet (Diethylcarbamazine citrate + Oxibendazole)
Trastuzumab Chemical_Formula
C6470H10012N1726O2013S42
Trastuzumab RX_link
http://www.rxlist.com/cgi/generic/trastuz.htm
Trastuzumab fda sheet
Trastuzumab msds (material safety sheet)
Trastuzumab Synthesis Reference
No information avaliable
Trastuzumab Molecular Weight
145531.5
Trastuzumab Melting Point
61 oC (FAB fragment), 71 oC (whole mAb)-Vermeer, A.W.P. & Norde, W., Biophys. J. 78:394-404 (2000).
Trastuzumab H2O Solubility
No information avaliable
Trastuzumab State
Liquid
Trastuzumab LogP
-0.415
Trastuzumab Dosage Forms
Solution (IV Infusion)
Trastuzumab Indication
For treatment of HER2-positive metatsatic breast cancer
Trastuzumab Pharmacology
Used in the treatment of HER2-positive breast cancer. HER2 protein overexpression is observed in 25%-30% of primary breast cancers.Trastuzumab has been shown, in both in vitro assays and in animals, to inhibit the proliferation of human tumorcells that overexpress HER2. It is a mediator of antibody dependent cellular cytotoxicity, in that the binding of the antibody to HER2 overexpressing cells leads to preferential cell death.
Trastuzumab Absorption
No information avaliable
Trastuzumab side effects and Toxicity
No information avaliable
Trastuzumab Patient Information
No information avaliable
Trastuzumab Organisms Affected
Humans and other mammals
