Simdax

Simdax Brand names, Simdax Analogs

Simdax Brand Names Mixture

No information avaliable

Simdax Chemical_Formula

C₁₄H₁₁Cl₂NO₂

Simdax RX_link

http://www.rxlist.com/cgi/generic3/meclofen.htm

Simdax fda sheet

Simdax msds (material safety sheet)

Simdax MSDS

Simdax Synthesis Reference

No information avaliable

Simdax Molecular Weight

295.02 g/mol

Simdax Melting Point

257 ^oC

Simdax H₂O Solubility

30 mg/L

Simdax State

Solid

Simdax LogP

4.998

Simdax Dosage Forms

Capsules (containing 50 mg or 100 mg meclofenamic acid as the sodium salt)

Simdax Indication

For the relief of mild to moderate pain, for the treatment of primary dysmenorrhea and for the treatment of idiopathic heavy menstrual blood loss. Also for relief of the signs and symptoms of acute and chronic rheumatoid arthritis and osteoarthritis.

Simdax Pharmacology

Meclofenamate is a nonsteroidal agent which has demonstrated anti-inflammatory, analgesic, and antipyretic activity in laboratory animals.

Simdax Absorption

Rapidly absorbed in man following single and multiple oral doses with peak plasma concentrations occurring in 0.5 to 2 hours. The concomitant administration of antacids (aluminum and magnesium hydroxides) does not interfere with absorption of meclofenamate. Unlike most NSAIDs, which when administered with food have a decrease in rate but not in extent of absorption, meclofenamic acid is decreased in both. It has been reported that following the administration of meclofenamate capsules one-half hour after a meal, the average extent of bioavailability decreased by 26%, the average peak concentration (C_max) decreased fourfold and the time to C_max was delayed by 3 hours.

Simdax side effects and Toxicity