Sertaconazol [Spanish] en es it fr

Sertaconazol [Spanish] Brand names, Sertaconazol [Spanish] Analogs

Sertaconazol [Spanish] Brand Names Mixture

  • No information avaliable

Sertaconazol [Spanish] Chemical_Formula

C20H15Cl3N2OS

Sertaconazol [Spanish] RX_link

http://www.rxlist.com/cgi/generic3/ertaczo.htm

Sertaconazol [Spanish] fda sheet

Sertaconazol_[Spanish] FDA

Sertaconazol [Spanish] msds (material safety sheet)

Sertaconazol [Spanish] Synthesis Reference

No information avaliable

Sertaconazol [Spanish] Molecular Weight

437.77 g/mol

Sertaconazol [Spanish] Melting Point

No information avaliable

Sertaconazol [Spanish] H2O Solubility

Practically insoluble

Sertaconazol [Spanish] State

Solid

Sertaconazol [Spanish] LogP

5.952

Sertaconazol [Spanish] Dosage Forms

Cream (2% contains 17.5 mg of sertaconazole)

Sertaconazol [Spanish] Indication

For the topical treatment of interdigital tinea pedis in immunocompetent patients 12 years of age and older, caused by Trichophyton rubrum, Trichophyton mentagrophytes, and Epidermophyton floccosum.

Sertaconazol [Spanish] Pharmacology

Sertaconazole is an imidazole/triazole type antifungal agent. Sertaconazole is a highly selective inhibitor of fungal cytochrome P-450 sterol C-14 α-demethylation via the inhibition of the enzyme cytochrome P450 14α-demethylase. This enzyme converts lanosterol to ergosterol, and is required in fungal cell wall synthesis. The subsequent loss of normal sterols correlates with the accumulation of 14 α-methyl sterols in fungi and may be partly responsible for the fungistatic activity of fluconazole. Mammalian cell demethylation is much less sensitive to fluconazole inhibition. Sertaconazole exhibits in vitro activity against Cryptococcus neoformans and Candida spp. Fungistatic activity has also been demonstrated in normal and immunocompromised animal models for systemic and intracranial fungal infections due to Cryptococcus neoformans and for systemic infections due to Candida albicans.

Sertaconazol [Spanish] Absorption

No information avaliable

Sertaconazol [Spanish] side effects and Toxicity

No information avaliable

Sertaconazol [Spanish] Patient Information

The patient should be instructed to:
  1. Use Sertaconazole Cream, 2%, as directed by the physician. The hands should be washed after applying the medication to the affected area(s). Avoid contact with the eyes, nose, mouth and other mucous membranes. Sertaconazole Cream, 2%, is for external use only.
  2. Dry the affected area(s) thoroughly before application, if you wish to use Sertaconazole Cream, 2%, after bathing.
  3. Use the medication for the full treatment time recommended by the physician, even though symptoms may have improved. Notify the physician if there is no improvement after the end of the prescribed treatment period, or sooner, if the condition worsens.
  4. Inform the physician if the area of application shows signs of increased irritation, redness, itching, burning, blistering, swelling or oozing.
  5. Avoid the use of occlusive dressings unless otherwise directed by the physician.
  6. Do not use this medication for any disorder other than that for which it was prescribed.

Sertaconazol [Spanish] Organisms Affected

Yeast and other fungi