Prochlorpemazine
Prochlorpemazine Brand names, Prochlorpemazine Analogs
- Bayer A 173
- Buccastem
- Compazine
- Capazine
- Chlormeprazine
- Chlorperazine
- Combid
- Compro
- Emelent
- Emetiral
- Eskatrol
- Kronocin
- Meterazin
- Meterazin Maleate
- Meterazine
- Nipodal
- Novamin
- Pasotomin
- Prochloroperazine
- Prochlorpemazine
- Prochlorperazin
- Prochlorperazine edisylate
- Prochlorperazine maleate
- Prochlorpromazine
- Procloperazine
- Proclorperazine
- Stemetil
- Tementil
- Temetid
- Vertigon
Prochlorpemazine Brand Names Mixture
- No information avaliable
Prochlorpemazine Chemical_Formula
C20H24ClN3S
Prochlorpemazine RX_link
http://www.rxlist.com/cgi/generic/prochlr.htm
Prochlorpemazine fda sheet
Prochlorpemazine msds (material safety sheet)
Prochlorpemazine Synthesis Reference
R. J. Horclois, U.S. Pat. 2,902,484 (1959)
Prochlorpemazine Molecular Weight
373.943 g/mol
Prochlorpemazine Melting Point
228oC
Prochlorpemazine H2O Solubility
Very slightly soluble
Prochlorpemazine State
Solid
Prochlorpemazine LogP
4.99
Prochlorpemazine Dosage Forms
Tablet; Spansule; Capsule; Vial; Suppository; Syrup
Prochlorpemazine Indication
For control of severe nausea and vomiting, also used in management of the manifestations of psychotic disorders.
Prochlorpemazine Pharmacology
Prochlorperazine is a piperazine phenothiazine related to high-potency neuroleptics such as perphenazine. It shares many of the actions and adverse effects of the antipsychotics.
Prochlorpemazine Absorption
Rapidly absorbed following oral administration
Prochlorpemazine side effects and Toxicity
Symptoms of central nervous system depression to the point of somnolence or coma. Agitation and restlessness may also occur. Other possible manifestations include convulsions, EKG changes and cardiac arrhythmias, fever and autonomic reactions such as hypotension, dry mouth and ileus; LD50=400mg/kg (orally in mice)
Prochlorpemazine Patient Information
Prochlorpemazine Organisms Affected
Humans and other mammals
