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Chlorperazine
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Chlorperazine Brand names, Chlorperazine Analogs

Chlorperazine Brand Names Mixture

  • No information avaliable

Chlorperazine Chemical_Formula

C20H24ClN3S

Chlorperazine RX_link

http://www.rxlist.com/cgi/generic/prochlr.htm

Chlorperazine fda sheet

Chlorperazine FDA

Chlorperazine msds (material safety sheet)

Chlorperazine Synthesis Reference

R. J. Horclois, U.S. Pat. 2,902,484 (1959)

Chlorperazine Molecular Weight

373.943 g/mol

Chlorperazine Melting Point

228oC

Chlorperazine H2O Solubility

Very slightly soluble

Chlorperazine State

Solid

Chlorperazine LogP

4.99

Chlorperazine Dosage Forms

Tablet; Spansule; Capsule; Vial; Suppository; Syrup

Chlorperazine Indication

For control of severe nausea and vomiting, also used in management of the manifestations of psychotic disorders.

Chlorperazine Pharmacology

Prochlorperazine is a piperazine phenothiazine related to high-potency neuroleptics such as perphenazine. It shares many of the actions and adverse effects of the antipsychotics.

Chlorperazine Absorption

Rapidly absorbed following oral administration

Chlorperazine side effects and Toxicity

Symptoms of central nervous system depression to the point of somnolence or coma. Agitation and restlessness may also occur. Other possible manifestations include convulsions, EKG changes and cardiac arrhythmias, fever and autonomic reactions such as hypotension, dry mouth and ileus; LD50=400mg/kg (orally in mice)

Chlorperazine Patient Information

Chlorperazine Organisms Affected

Humans and other mammals