Pimecrolimus

• Anti-Inflammatory Agents, Non-Steroidal
• Dermatologic Agents
• Enzyme Inhibitors
• Immunosuppressive Agents
• ATC:D11AX15

• Bitter salt
• Elliotts B Solution
• Epsom salt
• Epsom salts
• Hair salt
• Kieserite [as monohydrate]
• Magnesium Sulfate In Plastic Container
• Magnesium Sulfate, USP Grade
• Magnesium Sulphate Heptahydrate
• Magnesium Sulphate Hydrate
• Magnesium sulfate - dried
• Magnesium sulfate dried
• Magnesium sulfate heptahydrate
• Magnesium sulphate
• Magnesium sulfate anhydrous
• MgSO4
• Sal amarum
• Sal anglicum
• Sal catharticum
• Sal seidlitense
• Salts of England
• Sel d'angleterre

• No information avaliable

C₄₃H₆₈ClNO₁₁

http://www.rxlist.com/cgi/generic/elidel.htm

Pimecrolimus FDA

No information avaliable

810.453 g/mol

No information avaliable

No information avaliable

Solid

5.099

Cream

For treatment of mild to moderate atopic dermatitis.

Pimecrolimus is a chemical that is used to treat atopic dermatitis (eczema). Atopic dermatitis is a skin condition characterized by redness, itching, scaling and inflammation of the skin. The cause of atopic dermatitis is not known; however, scientists believe that it may be due to activation of the immune system by various environmental or emotional triggers. Scientists do not know exactly how pimecrolimus reduces the manifestations of atopic dermatitis, but pimecrolimus reduces the action of T-cells and mast cells which are part of the immune system and contribute to responses of the immune system. Pimecrolimus prevents the activation of T-cells by blocking the effects of chemicals (cytokines) released by the body that stimulate T-cells. Pimecrolimus also reduces the ability of mast cells to release chemicals that promote inflammation.

Because of the low systemic absorption of pimecrolimus following topical application the calculation of standard pharmacokinetic measures such as AUC, C_max, half-life, etc. cannot be reliably done.

Side effects include burning sensation, irritation, pruritus, erythema, and skin infections, at the application site.

Humans and other mammals