Pentamidine Isethionate en es it fr

Pentamidine Isethionate Brand names, Pentamidine Isethionate Analogs

Pentamidine Isethionate Brand Names Mixture

  • No information avaliable

Pentamidine Isethionate Chemical_Formula

C19H24N4O2

Pentamidine Isethionate RX_link

http://www.rxlist.com/cgi/generic3/pentam.htm

Pentamidine Isethionate fda sheet

Pentamidine Isethionate msds (material safety sheet)

Pentamidine_Isethionate MSDS

Pentamidine Isethionate Synthesis Reference

No information avaliable

Pentamidine Isethionate Molecular Weight

340.42 g/mol

Pentamidine Isethionate Melting Point

186.0 oC (decomposes)

Pentamidine Isethionate H2O Solubility

Complete

Pentamidine Isethionate State

Solid

Pentamidine Isethionate LogP

3.28

Pentamidine Isethionate Dosage Forms

Powder for solution

Pentamidine Isethionate Indication

For the treatment of pneumonia due to Pneumocystis carinii.

Pentamidine Isethionate Pharmacology

Pentamidine is an antiprotozoal agent. It is an aromatic diamidine, and is known to have activity against Pneumocystis carinii. The exact nature of its antiprotozoal action is unknown. in vitro studies with mammalian tissues and the protozoan Crithidia oncopelti indicate that the drug interferes with nuclear metabolism producing inhibition of the synthesis of DNA, RNA, phospholipids and proteins. Little is known about the drug's pharmacokinetics. The medication is also useful in Leishmaniasis and in prophylaxis against sleeping sickness caused by Trypanosoma brucei gambiense. Hydration before treatment lessens the incidence and severity of side effects, which include liver or kidney dysfunction, hypertension, hypotension, hypoglycemia, hypocalemia, leukopenia, thrombcytopenia, anemia, and allergic reaction. It is generally well-tolerated.

Pentamidine Isethionate Absorption

Absorbed poorly through the gastrointestinal tract and is usually administered parenterally.

Pentamidine Isethionate side effects and Toxicity

Symptoms of overdose include pain, nausea, anorexia, hypotension, fever, rash, bad taste in mouth, confusion/hallucinations, dizziness, and diarrhea.

Pentamidine Isethionate Patient Information

No information avaliable

Pentamidine Isethionate Organisms Affected

Pneumocystis carinii