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Metoprolol Brand names, Metoprolol Analogs

Metoprolol Brand Names Mixture


Metoprolol Chemical_Formula


Metoprolol RX_link

Metoprolol fda sheet

Metoprolol FDA

Metoprolol msds (material safety sheet)

Metoprolol MSDS

Metoprolol Synthesis Reference

A. E. Brandstorm et al., U.S. Pat. 3,873,600 (1975)

Metoprolol Molecular Weight

267.364 g/mol

Metoprolol Melting Point

120 oC (tartarate salt)

Metoprolol H2O Solubility

16.9 mg/mL

Metoprolol State


Metoprolol LogP


Metoprolol Dosage Forms


Metoprolol Indication

For the treatment of hypertension and angina pectoris.

Metoprolol Pharmacology

Metoprolol, a competitive, beta1-selective (cardioselective) adrenergic antagonist, is similar to atenolol in its moderate lipid solubility, lack of intrinsic sympathomimetic activity (ISA), and weak membrane stabilizing activity (MSA).

Metoprolol Absorption

Rapid and complete, 50%

Metoprolol side effects and Toxicity

LD50=5500 mg/kg (orally in rats), toxic effects include bradycardia, hypotension, bronchospasm, and cardiac failure. LD50=2090 mg/kg (orally in mice)

Metoprolol Patient Information

Metoprolol succinate is used to treat high blood pressure alone or in combination with other medications. This medication can also be used to treat a heart condition called angina. This particular formulation is an extended release product, meaning it can be taken once a day. This medication should be taken as directed, with a meal or right after a meal. The tablets should not be broken or crushed. Do not take a double dose if a dose is missed. This medication should not be stopped abruptly; it should be discontinued slowly over time. If you are taking this medication for high blood pressure, make sure to have your blood pressure checked regularly. If you ever have trouble breathing, call your physician immediately. The most common adverse effects are dizziness and tiredness. It is important to inform all your healthcare providers that you are taking this medication, especially before any surgeries or procedures.

Metoprolol Organisms Affected

Humans and other mammals