Metoprolol Tartrate

• Sympatholytics
• Antihypertensive Agents
• Antiarrhythmic Agents
• Adrenergic Agents
• ATC:C07AB02
• ATC:C07AB52

• Beloc
• Betaloc
• Lopressor HCT
• Lopresor
• Lopresoretic
• Lopressor
• Metoprolol Tartrate
• Metroprolol
• Prelis
• Selo-Zok
• Seloken
• Selopral
• Toprol
• Toprol-XL

• LOPRESSOR HCT

C₁₅H₂₅NO₃

http://www.rxlist.com/cgi/generic/metopxl.htm

Metoprolol_Tartrate FDA

Metoprolol_Tartrate MSDS

A. E. Brandstorm et al., U.S. Pat. 3,873,600 (1975)

267.364 g/mol

120 ^oC (tartarate salt)

16.9 mg/mL

Solid

2.477

Tablet

For the treatment of hypertension and angina pectoris.

Metoprolol, a competitive, beta1-selective (cardioselective) adrenergic antagonist, is similar to atenolol in its moderate lipid solubility, lack of intrinsic sympathomimetic activity (ISA), and weak membrane stabilizing activity (MSA).

Rapid and complete, 50%

LD₅₀=5500 mg/kg (orally in rats), toxic effects include bradycardia, hypotension, bronchospasm, and cardiac failure. LD₅₀=2090 mg/kg (orally in mice)

Metoprolol succinate is used to treat high blood pressure alone or in combination with other medications. This medication can also be used to treat a heart condition called angina. This particular formulation is an extended release product, meaning it can be taken once a day. This medication should be taken as directed, with a meal or right after a meal. The tablets should not be broken or crushed. Do not take a double dose if a dose is missed. This medication should not be stopped abruptly; it should be discontinued slowly over time. If you are taking this medication for high blood pressure, make sure to have your blood pressure checked regularly. If you ever have trouble breathing, call your physician immediately. The most common adverse effects are dizziness and tiredness. It is important to inform all your healthcare providers that you are taking this medication, especially before any surgeries or procedures.

Humans and other mammals