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Glycerylguaiacolate_carbamate
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Glycerylguaiacolate carbamate Brand names, Glycerylguaiacolate carbamate Analogs

Glycerylguaiacolate carbamate Brand Names Mixture

  • No information avaliable

Glycerylguaiacolate carbamate Chemical_Formula

C14H14N2O

Glycerylguaiacolate carbamate RX_link

http://www.rxlist.com/cgi/generic3/metopirone.htm

Glycerylguaiacolate carbamate fda sheet

Glycerylguaiacolate carbamate msds (material safety sheet)

Glycerylguaiacolate carbamate Synthesis Reference

No information avaliable

Glycerylguaiacolate carbamate Molecular Weight

226.274 g/mol

Glycerylguaiacolate carbamate Melting Point

50.5 oC

Glycerylguaiacolate carbamate H2O Solubility

Sparingly soluble

Glycerylguaiacolate carbamate State

Solid

Glycerylguaiacolate carbamate LogP

2.303

Glycerylguaiacolate carbamate Dosage Forms

Capsules for oral administration (250 mg)

Glycerylguaiacolate carbamate Indication

Used as a diagnostic drug for testing hypothalamic-pituitary ACTH function.

Glycerylguaiacolate carbamate Pharmacology

Metopirone is an inhibitor of endogenous adrenal corticosteroid synthesis.

Glycerylguaiacolate carbamate Absorption

Absorbed rapidly and well when administered orally. Peak plasma concentrations are usually reached 1 hour after administration.

Glycerylguaiacolate carbamate side effects and Toxicity

Oral LD50 in rats is 521 mg/kg. One case has been recorded in which a 6-year-old girl died after two doses of Metopirone, 2 g. Symptoms of overdose include cardiac arrhythmias, hypotension, dehydration, anxiety, confusion, weakness, impairment of consciousness, nausea, vomiting, epigastric pain, and diarrhea.

Glycerylguaiacolate carbamate Patient Information

Glycerylguaiacolate carbamate Organisms Affected

Humans and other mammals