PharmacyCodes



Duloxetine Hydrochloride en es it fr

Duloxetine Hydrochloride Brand names, Duloxetine Hydrochloride Analogs

Duloxetine Hydrochloride Brand Names Mixture

  • No information avaliable

Duloxetine Hydrochloride Chemical_Formula

C18H19NOS

Duloxetine Hydrochloride RX_link

http://www.rxlist.com/cgi/generic/cymbalta.htm

Duloxetine Hydrochloride fda sheet

Duloxetine_Hydrochloride FDA

Duloxetine Hydrochloride msds (material safety sheet)

Duloxetine_Hydrochloride MSDS

Duloxetine Hydrochloride Synthesis Reference

No information avaliable

Duloxetine Hydrochloride Molecular Weight

297.416 g/mol

Duloxetine Hydrochloride Melting Point

No information avaliable

Duloxetine Hydrochloride H2O Solubility

Slightly soluble

Duloxetine Hydrochloride State

Solid

Duloxetine Hydrochloride LogP

5.024

Duloxetine Hydrochloride Dosage Forms

Capsule

Duloxetine Hydrochloride Indication

For the treatment of major depressive disorder (MDD).

Duloxetine Hydrochloride Pharmacology

Duloxetine is in a class of medications called selective serotonin and norepinephrine reuptake inhibitors (SSNRIs) and primarily targets major depressive disorders (MDD) and stress urinary incontinence (SUI). Duloxetine is also used to treat pain and tingling caused by diabetic neuropathy (damage to nerves that can develop in people who have diabetes). Known also as LY248686, it is a potent dual inhibitor of serotonin (5-hydroxytryptamine, 5-HT) and norepinephrine (NE) reuptake, possessing comparable affinities in binding to NE and 5-HT transport sites. Interestingly, its behavior contrasts to most other dual-reuptake inhibitors. Furthermore, duloxentine lacks affinity for monoamine receptors within the central nervous system.

Duloxetine Hydrochloride Absorption

Orally administered duloxetine hydrochloride is well absorbed.

Duloxetine Hydrochloride side effects and Toxicity

Oral, rat LD50: 491 mg/kg for males and 279 mg/kg for females. Symptoms of overdose include tremors, convulsions, reduced activity, slow pupillary response, intermittent tremors, and rigidity.

Duloxetine Hydrochloride Patient Information

No information avaliable

Duloxetine Hydrochloride Organisms Affected

Humans and other mammals