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Cymbalta Brand names, Cymbalta Analogs

Cymbalta Brand Names Mixture

  • No information avaliable

Cymbalta Chemical_Formula

C18H19NOS

Cymbalta RX_link

http://www.rxlist.com/cgi/generic/cymbalta.htm

Cymbalta fda sheet

Cymbalta FDA

Cymbalta msds (material safety sheet)

Cymbalta MSDS

Cymbalta Synthesis Reference

No information avaliable

Cymbalta Molecular Weight

297.416 g/mol

Cymbalta Melting Point

No information avaliable

Cymbalta H2O Solubility

Slightly soluble

Cymbalta State

Solid

Cymbalta LogP

5.024

Cymbalta Dosage Forms

Capsule

Cymbalta Indication

For the treatment of major depressive disorder (MDD).

Cymbalta Pharmacology

Duloxetine is in a class of medications called selective serotonin and norepinephrine reuptake inhibitors (SSNRIs) and primarily targets major depressive disorders (MDD) and stress urinary incontinence (SUI). Duloxetine is also used to treat pain and tingling caused by diabetic neuropathy (damage to nerves that can develop in people who have diabetes). Known also as LY248686, it is a potent dual inhibitor of serotonin (5-hydroxytryptamine, 5-HT) and norepinephrine (NE) reuptake, possessing comparable affinities in binding to NE and 5-HT transport sites. Interestingly, its behavior contrasts to most other dual-reuptake inhibitors. Furthermore, duloxentine lacks affinity for monoamine receptors within the central nervous system.

Cymbalta Absorption

Orally administered duloxetine hydrochloride is well absorbed.

Cymbalta side effects and Toxicity

Oral, rat LD50: 491 mg/kg for males and 279 mg/kg for females. Symptoms of overdose include tremors, convulsions, reduced activity, slow pupillary response, intermittent tremors, and rigidity.

Cymbalta Patient Information

No information avaliable

Cymbalta Organisms Affected

Humans and other mammals