Carbamoylcholine-hydrochloride
Carbamoylcholine-hydrochloride Brand names, Carbamoylcholine-hydrochloride Analogs
- CB
- Carbachol USP27
- Carbachol chloride
- Carbachol hydrochloride
- Carbacholin
- Carbacholine
- Carbacholine chloride
- Carbacolina
- Carbaminocholine chloride
- Carbaminoylcholine chloride
- Carbamiotin
- Carbamoylcholine chloride
- Carbamoylcholine-hydrochloride
- Carbamylcholine chloride
- Carbastat
- Carbastat intraocular
- Carbochol
- Carbocholin
- Carbocholine
- Carboptic
- Carbyl
- Carcholin
- Choline carbamate chloride
- Choline chloride carbamate
- Choline chloride, carbamoyl-
- Choline chlorine carbamate
- Choline, chloride, carbamate
- Coletyl
- Doryl
- Isopto Carbachol
- Jestryl
- Karbachol
- Karbamoylcholin chlorid
- Lentin
- Lentine
- Miostat
- Mistura C
- Moryl
- P. V. Carbachol
- Rilentol
- Vasoperif
Carbamoylcholine-hydrochloride Brand Names Mixture
- No information avaliable
Carbamoylcholine-hydrochloride Chemical_Formula
C6H15N2O2+
Carbamoylcholine-hydrochloride RX_link
http://www.rxlist.com/cgi/generic2/carbachol.htm
Carbamoylcholine-hydrochloride fda sheet
Carbamoylcholine-hydrochloride msds (material safety sheet)
Carbamoylcholine-hydrochloride Synthesis Reference
No information avaliable
Carbamoylcholine-hydrochloride Molecular Weight
147.196 g/mol
Carbamoylcholine-hydrochloride Melting Point
210 oC
Carbamoylcholine-hydrochloride H2O Solubility
1 g/ml
Carbamoylcholine-hydrochloride State
Solid
Carbamoylcholine-hydrochloride LogP
-3.78
Carbamoylcholine-hydrochloride Dosage Forms
Liquid; Solution; Tablet
Carbamoylcholine-hydrochloride Indication
Primarily used in the treatment of glaucoma, but is also used during ophthalmic surgery.
Carbamoylcholine-hydrochloride Pharmacology
Carbachol is a potent cholinergic (parasympathomimetic) agent which produces constriction of the iris and ciliary body resulting in reduction in intraocular pressure. The exact mechanism by which carbachol lowers intraocular pressure is not precisely known. In the cat and rat, carbachol is well-known for its ability to induce rapid eye movement (REM) sleep when microinjected into the pontine reticular formation. Carbachol elicits this REM sleep-like state via activation of postsynaptic muscarinic cholinergic receptors (mAChRs).
Carbamoylcholine-hydrochloride Absorption
Not well absorbed in the gastro-intestinal tract, and does not cross the blood-brain barrier.
Carbamoylcholine-hydrochloride side effects and Toxicity
Oral, mouse: LD50 = 15 mg/kg; Oral, rat: LD50 = 40 mg/kg.
Carbamoylcholine-hydrochloride Patient Information
No information avaliable
Carbamoylcholine-hydrochloride Organisms Affected
Humans and other mammals
