P. V. Carbachol

P. V. Carbachol Brand names, P. V. Carbachol Analogs

P. V. Carbachol Brand Names Mixture

No information avaliable

P. V. Carbachol Chemical_Formula

C₆H₁₅N₂O₂+

P. V. Carbachol RX_link

http://www.rxlist.com/cgi/generic2/carbachol.htm

P. V. Carbachol fda sheet

P._V._Carbachol FDA

P. V. Carbachol msds (material safety sheet)

P._V._Carbachol MSDS

P. V. Carbachol Synthesis Reference

No information avaliable

P. V. Carbachol Molecular Weight

147.196 g/mol

P. V. Carbachol Melting Point

210 ^oC

P. V. Carbachol H₂O Solubility

1 g/ml

P. V. Carbachol State

Solid

P. V. Carbachol LogP

-3.78

P. V. Carbachol Dosage Forms

Liquid; Solution; Tablet

P. V. Carbachol Indication

Primarily used in the treatment of glaucoma, but is also used during ophthalmic surgery.

P. V. Carbachol Pharmacology

Carbachol is a potent cholinergic (parasympathomimetic) agent which produces constriction of the iris and ciliary body resulting in reduction in intraocular pressure. The exact mechanism by which carbachol lowers intraocular pressure is not precisely known. In the cat and rat, carbachol is well-known for its ability to induce rapid eye movement (REM) sleep when microinjected into the pontine reticular formation. Carbachol elicits this REM sleep-like state via activation of postsynaptic muscarinic cholinergic receptors (mAChRs).

P. V. Carbachol Absorption

Not well absorbed in the gastro-intestinal tract, and does not cross the blood-brain barrier.

P. V. Carbachol side effects and Toxicity

Oral, mouse: LD₅₀ = 15 mg/kg; Oral, rat: LD₅₀ = 40 mg/kg.

P. V. Carbachol Patient Information