Apormorphine
Category
Apormorphine Brand names, Apormorphine Analogs
Apormorphine Brand Names Mixture
Homeopathic Remedy Thc No. 48 Dps (Antimony Trisulfide + Apomorphine + Ipecac + Phosphorus + Pulsatilla)
Apormorphine Chemical_Formula
C17H17NO2
Apormorphine RX_link
http://www.rxlist.com/cgi/generic3/apokyn.htm
Apormorphine fda sheet
Apormorphine msds (material safety sheet)
Apormorphine Synthesis Reference
J. L. Neumeyer et al., J. Pharm. Sci. 59, 1850 (1970);
Apormorphine Molecular Weight
267.322 g/mol
Apormorphine Melting Point
No information avaliable
Apormorphine H2O Solubility
1.66E+004 mg/L
Apormorphine State
Solid
Apormorphine LogP
3.03
Apormorphine Dosage Forms
Subcutaneous solution (not for IV)
Apormorphine Indication
For the acute, intermittent treatment of hypomobility, off episodes (end-of-dose wearing off and unpredictable on/off episodes) associated with advanced Parkinson's disease.
Apormorphine Pharmacology
Apomorphine is a type of dopaminergic agonist, a morphine derivative which primarily affects the hypothalamic region of the brain. Drugs containing this substance are sometimes used in the treatment of Parkinson's disease or erectile dysfunction. In higher doses it is a highly effective emetic.
Apormorphine Absorption
100% following subcutaneous administration
Apormorphine Toxicity
LD50=0.6 mmoles/kg (mice, intraperitoneal)
Apormorphine Patient Information
Apormorphine Organisms Affected
Humans and other mammals
