L-Apomorphine
Category
L-Apomorphine Brand names, L-Apomorphine Analogs
L-Apomorphine Brand Names Mixture
Homeopathic Remedy Thc No. 48 Dps (Antimony Trisulfide + Apomorphine + Ipecac + Phosphorus + Pulsatilla)
L-Apomorphine Chemical_Formula
C17H17NO2
L-Apomorphine RX_link
http://www.rxlist.com/cgi/generic3/apokyn.htm
L-Apomorphine fda sheet
L-Apomorphine msds (material safety sheet)
L-Apomorphine Synthesis Reference
J. L. Neumeyer et al., J. Pharm. Sci. 59, 1850 (1970);
L-Apomorphine Molecular Weight
267.322 g/mol
L-Apomorphine Melting Point
No information avaliable
L-Apomorphine H2O Solubility
1.66E+004 mg/L
L-Apomorphine State
Solid
L-Apomorphine LogP
3.03
L-Apomorphine Dosage Forms
Subcutaneous solution (not for IV)
L-Apomorphine Indication
For the acute, intermittent treatment of hypomobility, off episodes (end-of-dose wearing off and unpredictable on/off episodes) associated with advanced Parkinson's disease.
L-Apomorphine Pharmacology
Apomorphine is a type of dopaminergic agonist, a morphine derivative which primarily affects the hypothalamic region of the brain. Drugs containing this substance are sometimes used in the treatment of Parkinson's disease or erectile dysfunction. In higher doses it is a highly effective emetic.
L-Apomorphine Absorption
100% following subcutaneous administration
L-Apomorphine Toxicity
LD50=0.6 mmoles/kg (mice, intraperitoneal)
L-Apomorphine Patient Information
L-Apomorphine Organisms Affected
Humans and other mammals
