Anakinra
Anakinra Brand names, Anakinra Analogs
Anakinra Brand Names Mixture
- No information avaliable
Anakinra Chemical_Formula
C759H1186N208O232S10
Anakinra RX_link
http://www.rxlist.com/cgi/generic/anakinra.htm
Anakinra fda sheet
Anakinra msds (material safety sheet)
Anakinra Synthesis Reference
No information avaliable
Anakinra Molecular Weight
17257.6
Anakinra Melting Point
No information avaliable
Anakinra H2O Solubility
No information avaliable
Anakinra State
Liquid
Anakinra LogP
-0.412
Anakinra Dosage Forms
Solution
Anakinra Indication
For treatment of adult rheumatoid arthritis
Anakinra Pharmacology
Used to treat rheumatoid arthritis, Kineret blocks the biologic activity of IL-1 by competitively inhibiting IL-1 binding to the interleukin-1 type I receptor (IL-1RI), which is expressed in a wide variety of tissues and organs.1 IL-1 production is induced in response to inflammatory stimuli and mediates various physiologic responses including inflammatory and immunological responses. Patients with rheumatoid arthritis have elevated levels of IL-1. The levels of the naturally occurring IL-1Ra in synovium and synovial fluid from rheumatoid arthritis (RA) patients are not sufficient to compete with the elevated amount of locally produced IL-1. Increasing the levels of IL-1Ra by artificial means reduces the negative effects (cartilage degradation, bone resorption) of IL-1.
Anakinra Absorption
No information avaliable
Anakinra side effects and Toxicity
No information avaliable
Anakinra Patient Information
BIOD00060.html
Anakinra Organisms Affected
Humans and other mammals
