Acibilin
Category
Acibilin Brand names, Acibilin Analogs
Acibilin Brand Names Mixture
No information avaliable
Acibilin Chemical_Formula
C10H16N6S
Acibilin RX_link
http://www.rxlist.com/cgi/generic/cimet.htm
Acibilin fda sheet
Acibilin msds (material safety sheet)
Acibilin Synthesis Reference
G. J. Durant et al.; U.S. Pat. 3,950,333 (1976)
Acibilin Molecular Weight
252.34 g/mol
Acibilin Melting Point
142 oC
Acibilin H2O Solubility
0.5 g/100 mL
Acibilin State
Solid
Acibilin LogP
0.879
Acibilin Dosage Forms
Tablets; Oral solution
Acibilin Indication
For the treatment and the management of acid-reflux disorders (GERD), peptic ulcer disease, heartburn, and acid indigestion
Acibilin Pharmacology
Cimetidine is a histamine H2-receptor antagonist. It reduces basal and nocturnal gastric acid secretion and a reduction in gastric volume, acidity, and amount of gastric acid released in response to stimuli including food, caffeine, insulin, betazole, or pentagastrin. It is used to treat gastrointestinal disorders such as gastric or duodenal ulcer, gastroesophageal reflux disease, and pathological hypersecretory conditions. Cimetidine inhibits many of the isoenzymes of the hepatic CYP450 enzyme system. Other actions of Cimetidine include an increase in gastric bacterial flora such as nitrate-reducing organisms.
Acibilin Absorption
Rapid 60-70%
Acibilin Toxicity
nausea, vomiting, diarrhea, increased saliva production, difficulty breathing, and a fast heartbeat.
Acibilin Patient Information
Acibilin Organisms Affected
Humans and other mammals