Tratul
Tratul Brand names, Tratul Analogs
Tratul Brand Names Mixture
- No information avaliable
Tratul Chemical_Formula
C10H16N6S
Tratul RX_link
http://www.rxlist.com/cgi/generic/cimet.htm
Tratul fda sheet
Tratul msds (material safety sheet)
Tratul Synthesis Reference
G. J. Durant et al.; U.S. Pat. 3,950,333 (1976)
Tratul Molecular Weight
252.34 g/mol
Tratul Melting Point
142 oC
Tratul H2O Solubility
0.5 g/100 mL
Tratul State
Solid
Tratul LogP
0.879
Tratul Dosage Forms
Tablets; Oral solution
Tratul Indication
For the treatment and the management of acid-reflux disorders (GERD), peptic ulcer disease, heartburn, and acid indigestion
Tratul Pharmacology
Cimetidine is a histamine H2-receptor antagonist. It reduces basal and nocturnal gastric acid secretion and a reduction in gastric volume, acidity, and amount of gastric acid released in response to stimuli including food, caffeine, insulin, betazole, or pentagastrin. It is used to treat gastrointestinal disorders such as gastric or duodenal ulcer, gastroesophageal reflux disease, and pathological hypersecretory conditions. Cimetidine inhibits many of the isoenzymes of the hepatic CYP450 enzyme system. Other actions of Cimetidine include an increase in gastric bacterial flora such as nitrate-reducing organisms.
Tratul Absorption
Rapid 60-70%
Tratul side effects and Toxicity
nausea, vomiting, diarrhea, increased saliva production, difficulty breathing, and a fast heartbeat.
Tratul Patient Information
Tratul Organisms Affected
Humans and other mammals
