Theo-Nite

Safety (MSDS) data for theophylline

Safety (MSDS) data for theophylline

Hazard: harmful


General

    Synonyms: 1,3-dimethylxanthine, 3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione, aminophylline, elixophylline, pseudotheophylline, theocin, theophyllin
    Use: diuretic, drug used in the treatment of shock, cardiac stimulant
    Molecular formula: C7H8N4O2
    CAS No: 58-55-9
    EINECS No:

Physical data

    Appearance: white crystalline powder
    Melting point: 272 - 274 C
    Boiling point:
    Vapour density:
    Vapour pressure:
    Density (g cm-3):
    Flash point:
    Explosion limits:
    Autoignition temperature:
    Water solubility: slight

Stability

    Stable. Incompatible with strong oxidizing agents.

Toxicology

    Toxic if swallowed or if absorbed into the body through cuts or scratches. Harmful if inhaled or absorbed through the skin. May affect CNS. Experimntal teratogen.

    Toxicity data
    (The meaning of any toxicological abbreviations which appear in this section is given here.)
    IMS-CHD TDLO 50 mg kg-1
    IVN-HMN TDLO 10 mg kg-1/d
    PAR-MAN LDLO 12 mg kg-1
    ORL-CHD LDLO 8.4 mg kg-1
    ORL-WMN TDLO 5 mg kg-1
    ORL-RAT LD50 244 mg kg-1
    IPR-RAT LD50 188 mg kg-1
    ORL-MUS LD50 255 mg kg-1
    IVN-MUS LD50 136 mg kg-1

    Risk phrases
    (The meaning of any risk phrases which appear in this section is given here.)
    R20 R21 R25.

Transport information

    (The meaning of any UN hazard codes which appear in this section is given here.)
    Non-hazardous for air, sea and road freight.

Personal protection

    Safety glasses, gloves.

    Safety phrases
    (The meaning of any safety phrases which appear in this section is given here.)

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This information was last updated on September 2, 2005. We have tried to make it as accurate and useful as possible, but can take no responsibility for its use, misuse, or accuracy. We have not verified this information, and cannot guarantee that it is up-to-date.