GLAXO INC -- IMITREX -- 6505-01-374-5873
===================== Product Identification =====================
Product ID:IMITREX
MSDS Date:02/02/1993
FSC:6505
NIIN:01-374-5873
MSDS Number: BVQHB
=== Responsible Party ===
Company Name:GLAXO INC
Address:5 MOORE DR
City:RESEARCH TRIANGLE PARK
State:NC
ZIP:27709
Country:US
Info Phone Num:919-248-2100
Emergency Phone Num:919-248-2100/2700
CAGE:34006
=== Contractor Identification ===
Company Name:GLAXO WELLCOME INC.
Address:5 MOORE DR
Box:13398
City:DURHAM
State:NC
ZIP:27709
Country:US
Phone:919-248-2100
CAGE:34006
============= Composition/Information on Ingredients =============
Ingred
Name:3-(2-(DIMETHYLAMINO)ETHYL)-N-METHYL-1H-INDOLE-5-METHANESULFONA
MIDE WITH SUCCINIC ACID(1:1)
CAS:103628-48-4
Other REC Limits:15MG/M3
===================== Hazards Identification =====================
Routes of Entry: Inhalation:YES Skin:NO Ingestion:YES
Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO
Health Hazards Acute and Chronic:INTRAVENOUS/INHAL/INGEST:MAY CAUSE
ELEVATED SYSTOLIC BLOOD PRESSURE.
Explanation of Carcinogenicity:THERE ARE NO INGREDIENTS ABOVE 0.1%
WHICH ARE IDENTIFIED AS CARCINOGENS BY NTP,IARC OR OSHA.
Effects of Overexposure:INTRAVENOUS/INGEST/INHAL:MAY CAUSE CHEST
PAIN(ANGINA),TREMOR,LACK OF COORDINATION,DILATION OF PUPILS AND
BLOOD VESSELS,SALIVATION,INCREASED HEART AND BREATHING RATES.
Medical Cond Aggravated by Exposure:PERSONS WITH PRE-EXISTING HEART
AILMENTS(HIGH BLOOD PRESSURE,CORONARY DISEASE) MAY BE AT INCREASED
RISK FROM EXPOSURE.
======================= First Aid Measures =======================
First Aid:SKIN:REMOVE CONTAMINATED CLOTHING;WASH WITH SOAP AND
WATER.EYES:FLUSH WITH WATER FOR 15 MINUTES.INHAL:REMOVE TO FRESH
AIR.GIVE OXYGEN OR ARTIFICIAL RESPIRATION IF NEEDED.INGEST:DO NOT
INDUCE VOMITING. GET PROMPT QUALIFIED MEDICAL ATTENTION.IF
CONSCIOUS,RINSE MOUTH WITH WATER.
===================== Fire Fighting Measures =====================
Flash Point:NONE
Extinguishing Media:WATER SPRAY,MULTI-PURPOSE DRY CHEMICAL.
Fire Fighting Procedures:USE A SELF-CONTAINED BREATHING APPARATUS AND
FULL PROTECTIVE EQUIPMENT.
Unusual Fire/Explosion Hazard:THE FINELY DISPURSED DUST FROM THIS
PRODUCT IS A FIRE OR EXPLOSION HAZARD IN THE PRESENCE OF SOURCES OF
IGNITION.
================== Accidental Release Measures ==================
Spill Release Procedures:USE PROPER PROTECTIVE AND RESPIRATORY
EQUIPMENT.SWEEP OR VACUUM WITH A HEPA VACUUM.DO NOT STIR UP
DUST.PLACE IN AN APPROPRIATE CONTAINER FOR DISPOSAL.CLEAN SPILL
AREA.
Neutralizing Agent:NONE
====================== Handling and Storage ======================
Handling and Storage Precautions:STORE IN A COOL,DRY,WELL-VENTILATED
PLACE.KEEP CONTAINER CLOSED WHEN NOT IN USE.AVOID CREATING DUST.
Other Precautions:FOLLOW LABEL DIRECTIONS.AVOID BREATHING DUST.AVOID
SKIN AND EYE CONTACT.
============= Exposure Controls/Personal Protection =============
Respiratory Protection:WHERE ENVIRONMENTAL CONTROLS ARE LACKING OR IN
ENCLOSED SPACES USE A NIOSH/MSHA APPROVED RESPIRATOR FOR DUST.
Ventilation:USE LOCAL EXHAUST.
Protective Gloves:IMPERVIOUS
Eye Protection:DUST-PRROF GOGGLES.
Other Protective Equipment:PROTECTIVE CLOTHING,AS NEEDED.PROVIDE A
LOCAL EYE WASH STATION AND SAFETY SHOWER.
Work Hygienic Practices:USE REASONABLE CARE IN HANDLING THIS
PRODUCT.WASH HANDS AFTER USE AND BEFORE EATING.
Supplemental Safety and Health
TIR REPORTS THAT THIS ITEM IS CONTAINED IN A SYRINGE AT 6MG/0.5ML AND
THAT THE SYRINGE CONTAINS 1 ML.WORKERS EXPOSED TO DUST SHOULD
CHANGE CLOTHES AND SHOWER.
================== Physical/Chemical Properties ==================
HCC:N1
Melt/Freeze Pt:M.P/F.P Text:329F,165C
Solubility in Water:APPRECIABLE
Appearance and Odor:POWDER;WHITE TO OFF-WHITE.ODOR NOT REPORTED.TIR
REPORTS ITEM IS IN A SYRINGE.
================= Stability and Reactivity Data =================
Stability Indicator/Materials to Avoid:YES
MANUFACTURER STATES NONE KNOWN.
Stability Condition to Avoid:HIGH HEAT;DECOMPOSES ENDOTHERMICALLY(TAKES
IN HEAT).
Hazardous Decomposition Products:CORROSIVE OXIDES OF NITROGEN AND
SULFUR.
==================== Disposal Considerations ====================
Waste Disposal Methods:DISPOSE OF IN ACCORDANCE WITH FEDERAL,STATE AND
LOCAL REGULATIONS.MFR SUGGESTS INCINERATION.
Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.