SK-Digoxin

ELKINS-SINN INC -- DIGOXIN INJECTION
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MSDS Safety Information
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FSC: 6505
NIIN: 00-147-4974
MSDS Date: 09/25/1992
MSDS Num: BWMPD
Product ID: DIGOXIN INJECTION
MFN: 01
Responsible Party
Cage: 51968
Name: ELKINS-SINN INC
Address: 2 ESTERBROOK LN
City: CHERRY HILL NJ 08003
Info Phone Number: 609-424-3700 / 800-257-8349
Emergency Phone Number: 609-424-3700/800-424-9300(CHEMTREC)
Review Ind: Y
Published: Y
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Contractor Summary
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Cage: 51968
Name: ELKINS-SINN INC
Address: 2 ESTERBROOK LANE
City: CHERRY HILL NJ 08003-4099
Phone: 800-257-8349/609-424-3700
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Item Description Information
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Item Name: DIGOXIN INJECTION,USP
Specification Number: UNKNOWN
Type of Container: AMPUL
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Ingredients
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Cas: 20830-75-5
RTECS #: IH6125000
Name: DIGOXIN (SARA III)
% Wt: 0.02
Other REC Limits: NONE RECOMMENDED
OSHA PEL: NOT ESTABLISHED
ACGIH TLV: NOT ESTABLISHED
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Cas: 57-55-6
RTECS #: TY2000000
Name: PROPYLENE GLYCOL
% Wt: >1
Other REC Limits: NONE RECOMMENDED
OSHA PEL: NOT ESTABLISHED
ACGIH TLV: NOT ESTABLISHED
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Cas: 64-17-5
RTECS #: KQ6300000
Name: ETHYL ALCOHOL (ETHANOL)
% Wt: >1
Other REC Limits: NONE RECOMMENDED
OSHA PEL: 1000 PPM
ACGIH TLV: 1000 PPM; 9394
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Cas: 7732-18-5
RTECS #: ZC0110000
Name: WATER
% Wt: >1
Other REC Limits: NONE RECOMMENDED
OSHA PEL: NOT ESTABLISHED
ACGIH TLV: NOT ESTABLISHED
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Health Hazards Data
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LD50 LC50 Mixture: LD50 ORAL,MOUSE=17780UG/KG FOR DIGOXIN
Route Of Entry Inds - Inhalation: NO
Skin: NO
Ingestion: YES
Carcinogenicity Inds - NTP: NO
IARC: NO
OSHA: NO
Effects of Exposure: DIGOXIN:INGEST:HIGHLY TOXIC.CARDIAC FAILURE,PULM
CONGESTIN,EXCRETED IN BREAST MILK,CROSSES PLACENTAL BARRIER,FETAL TOXICITY
& NEONATAL DEATH,SUDDEN DEATH.SKIN/INHAL:NO DATA AVAILABLE.HOWEVER SKIN
RASH MAY OCCUR AS RARE SIDE EFFECT FROM INGEST.EYE:25MG/100ML 3X/DAY CAUSED
INJURY OF CORNEA-REVERSIBLE WHEN DISCONTINUED.
Explanation Of Carcinogenicity: PER MSDS:CARCINOGEN STATUS:NONE.
Signs And Symptions Of Overexposure: INGEST:NAU,SALV,VOMIT,DIA,ABD
PAIN/DISCOMFORT,ANOREXIA,MUSCULAR
WEAK,FTG,DROW,HEAD,MALAISE,VERTIGO,IRRITABILITY,FALL IN BLOOD PRESSURE,IRREG
PULSE,COLD EXTREMITIES,NEURALGIC PAIN OF LOWER 3RD FACE,MEN TAL
DEPRESS,PERSONALITY CHANGES,DEFECTSIN MEM/CONCEN,DELERIUM,HALU,VIS DIST,FRANK
PSYCHOSIS,ANEMIA,HEART PROBLEMS.
Medical Cond Aggravated By Exposure: POISONING MAY AFFECT HEART & CNS.
@RISK ARE PERSONS W/RENAL INSUFFICIENCY,HYPOTHYROIDISM,HEART
DISORDERS.INTERACTIONS W/MEDICATINS HAVE BEEN REPORTED.
First Aid: INHAL:REMOVE TO FRESH AIR IMMED.STOP BREATH PERFORM ART RESP.KEEP
WARM/RESTED.TREAT SYMPTOM/SUPPORT.SKIN:REMOVE CONTAMIN CLOTH/SHOES IMMED.WASH
SKIN W/SOAP/MILD DETERG & LG AMTS OF WATER 15-20MINS.EYE :WASH IMMED W/LG
AMTS OF WATER OR NORMAL SALINE OPENING EYELIDS 15-20MINS.INGEST:IF CONSC/NOT
CONVUL REMOVE BY THOROUGH GASTRIC LAVAGE OR INDUCE EMESIS W/SYRUP OF
IPECAC.IN ALL CASES GET MED ATTN IMME
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Handling and Disposal
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Spill Release Procedures: SHUT OFF IGN SOURCES.STOP LEAK W/O RISK.USE
WATERSPRAY TO REDUCE VAP.SMALL:TAKE UP SAND/OTHER ABSORBENT MATL.PLACE INTO
CNTNR FOR DISPOSAL.LG:DIKE AHEAD OF SPILL FOR DISPOSAL LATER.NO
SMOKING/FLAME/FL ARES.KEEP UNNECESSARY PEOPLE AWAY.ISOLATE AREA.
Waste Disposal Methods: OBSERVE ALL LOCAL, STATE AND FEDERAL REGULATIONS WHEN
DISOSING OF SUBSTANCE. FOR ASSISTANCE CONTACT DISTRICT DIR OF EVIRONMENTAL
PROTECTION AGENCY.
Handling And Storage Precautions: OBSERVE ALL LOC/STATE/FED REGS WHEN STORING
SUBSTANCE.FOR ASSISTANCE CONTACT DISTRICT DIR OF EPA.STORE IAW
29CFR1910.STORE AWAY FROM INCOMPATIBLE SUB
Other Precautions: BOND/GROUND:STUBSTANCES IN PRODUCTION AREAS W/LOW
ELECTROCONDUCTIVITY WHICH MAY BE IGNITED BY ELECTROSTATIC SPARKS SHOULD BE
STORED IN CNTRNS WHICH MEET BONDING/GROUNDING GUIDELINES SPECIFIED IN NFPA
77-1983 RECOMMENDED PRACT ON STATIC ELEC
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Fire and Explosion Hazard Information
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Flash Point Text: 129F,54C
Extinguishing Media: DRY CHEMICAL, CARBON DIOXIDE, WTER SPRAY OR
ALCOHOL-RESISTANT FOAM.LG FIRES:WATER SPRAY,FOG,ALCOHOL-RESISTANT FOAM.
Fire Fighting Procedures: MOVE CNTNR FROM FIRE AREA W/O RISK.COOL CNTNRS SIDES
THAT ARE EXPO TO FLAMES W/WATER TIL WELL AFT FIRE IS OUT.CARGO AREA FIRE USE
UNMANNED HOSE (SUPPELMENTAL)
Unusual Fire/Explosion Hazard: VAP-AIR MIX EXPLO >FLASH PT.MOD FIRE HAZ WHEN
EXPO TO HEAT/FLAME.VAP EXPLO/POISONOUS.DO NOT ALLOW UNNECESASRY PEOPLE IN
AREA.CNTNR MAY VIO RUPTURE.TRAVEL DISTAN
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Control Measures
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Respiratory Protection: SPECIFIC RESP SELECTED MUST BE BASED ON CONTAMIN LEVELS
IN WORKPLACE,ON SPECIFIC OPERATION,NOT EXCEED WORKING LIMITS OF RESP,&
APPROVED BY NIOSH/MSHA.
Ventilation: PROVIDE LOCAL EXHAUST VENTILATION &/OR GENERAL DILUTION
VENTILATION TO MEET PUBLISHED EXPOSURE LIMITS.
Protective Gloves: NOT REQUIRED BUT RECOMMENDED.
Eye Protection: SPLASH-ROOF SAF GLASSES
Other Protective Equipment: NOT REQUIRED.AVOI DREPEATED/PROLONGED CONTACT WITH
SUBSTANCE.
Work Hygienic Practices: WASH HANDS AFT HANDLING. LAUNDER CONTAMIN CLOTHING
PRIOR TO REUSE. WASH SHOES PRIOR TO REUSE.
Supplemental Safety and Health: FIREFIGHTING:HOSE HOLDER/MONITOR NOZZ;IF
IMPOSSIBLE W/D FROM AREA & LET BURN.EXTINGUISH ONLY IF LFOW CAN BE
STOPPED;USE WATER INFLOODING AMTS AS FOG.SOLID STREAMS MAY NOT BE
EFFECTIVE.COOL CNTNRS W/FL OODING AMTS OF WATER.APPLY FROM AS FAR DISTANCE AS
POSSIBLE.AVOID BREATH VAP,KEEP UPWIND.
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Physical/Chemical Properties
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HCC: F4
Appearance and Odor: CLEAR, COLORLESS SOLUTION.
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Reactivity Data
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Stability Indicator: YES
Stability Condition To Avoid: CONTACT W/HEAT/SPARKS/FLAMES/OTHER IGN SOURCES.DO
NOT OVERHEAT CNTNRS.
Materials To Avoid: MAY BE INCOMPATIBLE WITH ACIDS, BASES, AND OXIDIZERS.
Hazardous Decomposition Products: THERMAL DECOMPOSITION MAY RELEASE TOXIC &/OR
HAZARDOUS GASES.
Hazardous Polymerization Indicator: NO
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Toxicological Information
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Ecological Information
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MSDS Transport Information
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Regulatory Information
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Other Information
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Transportation Information
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Responsible Party Cage: 51968
Trans ID NO: 50901
Product ID: DIGOXIN INJECTION
MSDS Prepared Date: 09/25/1992
Review Date: 03/03/1995
MFN: 1
Tech Entry NOS Shipping Nm: FLAMMABLE LIQUID, N.O.S. (ETHYL ALCOHOL >1%,
PROPYLENE GLYCOL >1%, DIGOXIN 0.02%)
Net Unit Weight: UNKNOWN
Multiple KIT Number: 0
Review IND: Y
Type Of Container: AMPUL
Additional Data: PER TIR:UNIT PKG TYP:BOX.
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Detail DOT Information
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DOT PSN Code: GJL
Symbols: G
DOT Proper Shipping Name: FLAMMABLE LIQUIDS, N.O.S.
Hazard Class: 3
UN ID Num: UN1993
DOT Packaging Group: III
Label: FLAMMABLE LIQUID
Special Provision: B1,B52,T7,T30
Packaging Exception: 150
Non Bulk Pack: 203
Bulk Pack: 242
Max Qty Pass: 60 L
Max Qty Cargo: 220 L
Vessel Stow Req: A
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Detail IMO Information
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IMO PSN Code: HIA
IMO Proper Shipping Name: FLAMMABLE LIQUID, N.O.S. o
IMDG Page Number: 3345
UN Number: 1993
UN Hazard Class: 3.3
IMO Packaging Group: III
Subsidiary Risk Label: -
EMS Number: 3-07
MED First Aid Guide NUM: T
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Detail IATA Information
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IATA PSN CA
IATA UN ID Num: 1993
IATA Proper Shipping Name: FLAMMABLE LIQUID, N.O.S. *
IATA UN Class: 3
IATA Label: FLAMMABLE LIQUID
UN Packing Group: III
Packing Note Passenger: 309
Max Quant Pass: 60L
Max Quant Cargo: 220L
Packaging Note Cargo: 310
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Detail AFI Information
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AFI PSN CA
AFI Symbols: *
AFI Proper Shipping Name: FLAMMABLE LIQUIDS, N.O.S.
AFI Hazard Class: 3
AFI UN ID NUM: UN1993
AFI Packing Group: III
Special Provisions: P5
Back Pack Reference: A7.3
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HAZCOM Label
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Product ID: DIGOXIN INJECTION
Cage: 51968
Company Name: ELKINS-SINN INC
Street: 2 ESTERBROOK LANE
City: CHERRY HILL NJ
Zipcode: 08003-4099
Health Emergency Phone: 609-424-3700/800-424-9300(CHEMTREC)
Label Required IND: Y
Date Of Label Review: 03/03/1995
Status Code: C
Label Date: 03/03/1995
Origination Code: F
Skin Protection IND: YES
Signal Word: DANGER
Health Hazard: Severe
Contact Hazard: Slight
Fire Hazard: Moderate
Reactivity Hazard: None
Hazard And Precautions: DIGOXIN:INGEST:HIGHLY TOXIC.CARD FAIL,PULM
CONGEST,EXCRETED IN BREAST MILK,CROSSES PLACENTAL BARRIER,FETAL
TOXICITY/NEONATAL DEATH,SUD DEATH.SKIN/INHAL:NO DATA AVAIL;SKIN RASH OCCURS
AS RARE SIDE EFFE CT FRM INGEST.EYE:25MG/100ML 3XDAY CAUSE CORNEAL
INJURY-REVER WHEN DISCONTD.TARGORG:HEART/CNS/KID/EYE/GI.1STAID:INHAL:MOVE TO
FRESH AIR.STOP BREATH GIVE ART RESP.KEEP WARM/RESTED.TREAT SYMP/SUPP.SKIN:
REMOVE CONTAMIN CLOTH/SHOES.WASH W/SOAP/MILD DETERG/LOTS OF WATER
15-20MIN.EYE:WASH W/LOTS OF WATER/NOR SALINE OPEN EYELIDS 15-20MIN.INGEST:IF
CONSC/NOT CONVUL REMOVE BY GASTRIC LAVAGE/INDUCE EMESIS W /SYRUP OF IPECAC.IN
ALL CASES GET MED ATTN IMMED.
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information is formulated for use by elements of the Department of Defense.
The United States of America in no manner whatsoever expressly or implied
warrants, states, or intends said information to have any application, use or
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particular situation regardless of similarity to a corresponding Department
of Defense or other government situation.