Ranidine

GLAXO INC -- RANITIDINE HYDROCHLORIDE -- 6850-00F039324
=====================  Product Identification  =====================

Product ID:RANITIDINE HYDROCHLORIDE
MSDS Date:10/01/1988
FSC:6850
NIIN:00F039324
MSDS Number: BWWTF
=== Responsible Party ===
Company Name:GLAXO INC
Address:5 MOORE DR
City:RESEARCH TRIANGLE PARK
State:NC
ZIP:27709-5000
Country:US
Info Phone Num:919-248-2100/2354
Emergency Phone Num:919-248-2100/2700
CAGE:34006
=== Contractor Identification ===
Company Name:GLAXO WELLCOME INC.
Address:5 MOORE DR
Box:13398
City:DURHAM
State:NC
ZIP:27709
Country:US
Phone:919-248-2100
CAGE:34006

=============  Composition/Information on Ingredients  =============

Ingred Name:RANITIDINE HYDROCHLORIDE			      *95-1*
CAS:70956-04-6
RTECS #:KM6557000
Fraction by Wt: 100%
OSHA PEL:0.05 MG/M3

=====================  Hazards Identification  =====================

Routes of Entry: Inhalation:NO	Skin:NO  Ingestion:NO
Reports of Carcinogenicity:NTP:NO    IARC:NO	OSHA:NO
Health Hazards Acute and Chronic:SKIN: IRRITATION, SENSITIZATION.
    INHALATION: IRRITATION OF THE MUCOUS MEMBRANES. EYES: IRRITATION.
    INGESTION: ADVERSE EFFECTS THAT HAVE BEEN OBSERVED W/RAINITIDINE
    USED CLINICALLY ARE REVERSIBLE INFLA MMATION OF THE LIVER WHICH MAY
    BE ACCOMPANIED BY JAUNDICE.
Explanation of Carcinogenicity:NONE
Effects of Overexposure:IRRITATION, RASH, SHORTNESS OF BREATH,
    WHEEZING, ITCHY RASH, NASAL CONGESTION, RUNNY NOSE, HEADACHE,
    JAUNDICE.

=======================  First Aid Measures  =======================

First Aid:EYES: FLUSH W/LARGE AMOUNTS OF WATER. SKIN: WASH W/SOAP &
    WATER. INHALATION: REMOVE TO FRESH AIR. GIVE OXYGEN/CPR IF NEEDED.
    INGESTION: RINSE MOUTH, GIVE LARGE QUANTITIES OF WATER & ENCOURAGE
    VOMITING . OBTAIN MEDICAL ATTENTION IN ALL CASES.

=====================  Fire Fighting Measures  =====================

Extinguishing Media:WATER SPRAY, FOAM, MULTI-PURPOSE DRY CHEMICAL
Fire Fighting Procedures:WEAR FULL PROTECTIVE CLOTHING & USE A SELF
    CONTAINED BREATHING APPARATUS.
Unusual Fire/Explosion Hazard:AS W/ANY ORGANIC DUST, THERE IS POTENTIAL
    FOR EXPLOSION WHEN SUSPENDED IN AIR IN HIGH CONCENTRATIONS.

==================  Accidental Release Measures  ==================

Spill Release Procedures:WEAR FULL PROTECTIVE EQUIPMENT. COLLECT BY
    CAREFULLY SWEEPING/VACUUMING W/HEPA FILTERED VACUUM & PLACE IN
    LABELED, SEALED CONTAINER FOR REUSE/DISPOSAL. WASH AREA W/WATER
    AFTER VACUUMING.

======================	Handling and Storage  ======================

Handling and Storage Precautions:USE PRACTICES THAT WILL MINIMIZE
    GENERATION OF DUST.
Other Precautions:AVOID BODY CONTACT.

=============  Exposure Controls/Personal Protection  =============

Respiratory Protection:RECOMMENDED BY NIOSH/MSHA.
Ventilation:LOCAL EXHAUST VENTILATION
Protective Gloves:REQUIRED
Eye Protection:REQUIRED
Work Hygienic Practices:REMOVE/LAUNDER CONTAMINATED CLOTHING BEFORE
    REUSE.
Supplemental Safety and Health

==================  Physical/Chemical Properties  ==================

Melt/Freeze Pt:M.P/F.P Text:272F
Solubility in Water:COMPLETE
Appearance and Odor:OFF-WHITE TO PALE YELLOW COLORED POWDER
    W/CHARACTERISTIC SULFUR-LIKE ODOR

=================  Stability and Reactivity Data  =================

Stability Indicator/Materials to Avoid:YES
Stability Condition to Avoid:EXTREME HEAT, TEMP >300F.
Hazardous Decomposition Products:TOXIC/CORROSIVE VAPORS, CHLORIDES,
    OXIDES OF NITROGEN & SULFUR

====================  Disposal Considerations  ====================

Waste Disposal Methods:INCINERATE AT AN APPROVED FACILITY IAW/FEDERAL,
    STATE & LOCAL REGULATIONS.

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