FUJISAWA INC (FORMERLY LYPHOMED INC) -- PENTAMIDINE ISETHIONATE -- 6505-00F039436
===================== Product Identification =====================
Product ID:PENTAMIDINE ISETHIONATE
MSDS Date:02/17/1988
FSC:6505
NIIN:00F039436
MSDS Number: BWWYV
=== Responsible Party ===
Company Name:FUJISAWA INC (FORMERLY LYPHOMED INC)
Address:2020 RUBY
City:MELROSE PARK
State:IL
ZIP:60160-5000
Country:US
Info Phone Num:708-450-7569/7500
Emergency Phone Num:708-450-7569/7500
CAGE:GO395
=== Contractor Identification ===
Company Name:FUJISAWA INC (FORMERLY LYPHOMED INC)
Address:2020 RUBY
City:MELROSE PARK
State:IL
ZIP:60160-5000
Country:US
Phone:708-450-7569/7500
CAGE:GO395
Company Name:LYPHOMED INC DIV OF FUJISAWA USA INC
Address:2020 RUBY ST
Box:City:MELROSE PARK
State:IL
ZIP:60160-1112
Country:US
Phone:312-345-6170
CAGE:60567
============= Composition/Information on Ingredients =============
Ingred Name:PENTAMIDINE ISETHIONATE
CAS:140-64-7
RTECS #:CV6500000
===================== Hazards Identification =====================
Routes of Entry: Inhalation:YES Skin:YES Ingestion:YES
Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO
Health Hazards Acute and Chronic:SEVERE ADVERSE REACTIONS HAVE BEEN
REPORTED SUCH AS: CARDIA ARRHYTHMIAS/DIABETES MELLITUS/ELEVATED
SERUM CREATININE/STERILE
ABSCESS/LEUKOPENIA/HYPOGLYCEMIA/HYPOTENSION/ACUTE RENAL
FAILURE/HYPOCALCEMIA /STEVENS-JOHNSON SYNDROME/VENTRICULAR
TACHYCARDIA/INDURATION AT THE SITE OF IM INJECTION/ELEVATED LIVER
FUNCTION (SUPP)
Explanation of Carcinogenicity:NONE
Effects of Overexposure:PAIN, NAUSEA, ANOREXIA, HYPOTENSION, FEVER,
RASH, BAD TASTE IN MOUTH, CONFUSION/HALLUCINATIONS, DIZZINESS,
DIARRHEA
======================= First Aid Measures =======================
First Aid:INHALATION: REMOVE TO FRESH AIR. INGESTION: FLUSH MOUTH OUT
W/WATER. SKIN/EYES: FLUSH W/WATER. OBTAIN MEDICAL ATTENTION IN ALL
CASES.
===================== Fire Fighting Measures =====================
Extinguishing Media:DRY CHEMICAL, CO2/FOAM AS APPROPRIATE FOR
SURROUNDING FIRE & MATERIALS.
Fire Fighting Procedures:USE SELF CONTAINED BREATHING APPARATUS &
PROTECTIVE CLOTHING.
Unusual Fire/Explosion Hazard:COMBUSTIBLE. EMITS TOXIC FUMES WHEN
HEATED TO DECOMPOSITION.
================== Accidental Release Measures ==================
Spill Release Procedures:WEAR PERSONAL PROTECTIVE EQUIPMENT. VACUUM
W/VACUUM CLEANER HAVING A HIGH EFFICIENCY PARTICULATE (HEPA)
FILTER/ABSORB LIQUID W/PAPER TOWELS. WIPE WORKING SURFACES TO
DRYNESS, THEN WASH W/SOAP & WATER.
====================== Handling and Storage ======================
Handling and Storage Precautions:DRY POWDER MATERIAL IS ASSUMED TO BE
COMBUSTIBLE. GROUND MECHANICAL EQUIPMENT IN CONTACT W/DRY MATERIAL
TO DISSIPATE BUILDUP OF STATIC ELECTRICITY.
Other Precautions:WHEN HANDLING PHARMACEUTICAL PRODUCTS, AVOID ALL
CONTACT & INHALATION OF DUST, FUMES, MISTS/VAPORS ASSOCIATED W/THE
PRODUCT.
============= Exposure Controls/Personal Protection =============
Respiratory Protection:USE NIOSH APPROVED RESPIRATOR
Ventilation:LOCAL EXHAUST
Protective Gloves:DISPOSABLE SURGICAL LATEX
Eye Protection:SAFETY GOGGLES
Other Protective Equipment:DISPOSABLE PROTECTIVE APPAREL
Work Hygienic Practices:REMOVE/LAUNDER CONTAMINATED CLOTHING BEFORE
REUSE.
Supplemental Safety and Health
PENTAM 300 (STERILE PENTAMIDINE ISETHIONATE) IS A WHITE, NONPYROGENIC,
LYOPHILIZED POWDER. HEALTH HAZ CONT'D: ANEMIA, NEURALGIA,
THROMBOCYTOPENIA, HYPERKALEMIA, PHLEBITIS. ONE PATIENT OUT OF 424
DEVEL OPED THE FOLLOWING ADVERSE REACTIONS: HYPOCALCEMIA,
BRONCHOSPASM, HYPERGLYCEMIA.
================== Physical/Chemical Properties ==================
Solubility in Water:COMPLETE
Appearance and Odor:WHITE, LYOPHILIZED POWDER W/NO ODOR
================= Stability and Reactivity Data =================
Stability Indicator/Materials to Avoid:YES
Stability Condition to Avoid:LIGHT, HEAT
Hazardous Decomposition Products:TOXIC FUMES
==================== Disposal Considerations ====================
Waste Disposal Methods:WASTE SHOULD BE DISPOSED OF IN ACCORDANCE
W/LOCAL, STATE & FEDERAL REGULATIONS.
Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.