Paxane

HOFFMAN-LA ROCHE INC -- DALMANE-30MG;FLURAZEPAM HYDROCHLORIDE -- 6505-00-400-7294
=====================  Product Identification  =====================

Product ID:DALMANE-30MG;FLURAZEPAM HYDROCHLORIDE
MSDS Date:10/31/1985
FSC:6505
NIIN:00-400-7294
MSDS Number: BTHMR
=== Responsible Party ===
Company Name:HOFFMAN-LA ROCHE INC
Address:340 KINGSLAND ST
City:NUTLEY
State:NJ
ZIP:07110-1141
Country:US
Info Phone Num:201-235-2323
Emergency Phone Num:201-235-2323
CAGE:04493
=== Contractor Identification ===
Company Name:HOFFMAN-LA ROCHE INC
Address:340 KINGSLAND ST
City:NUTLEY
State:NJ
ZIP:07110-1141
Country:US
Phone:201-235-2323
CAGE:04493

=============  Composition/Information on Ingredients  =============

Ingred Name:FLURAZEPAM HYDROCHLORIDE,30 MG PER TABLET
CAS:1172-18-5
RTECS #:DF0875000
Other REC Limits:NONE RECOMMENDED

=====================  Hazards Identification  =====================

LD50 LC50 Mixture:ORAL LD50 (RABBIT) IS 368MG/KG/5DAYS
Routes of Entry: Inhalation:YES  Skin:NO  Ingestion:YES
Reports of Carcinogenicity:NTP:NO    IARC:NO	OSHA:NO
Health Hazards Acute and Chronic:INGEST/INHAL:MAY CAUSE CNS DEPRESSION.
Explanation of Carcinogenicity:THERE ARE NO INGREDIENTS ABOVE 0.1%
    WHICH ARE IDENTIFIED AS CARCINOGENS BY NTP,IARC OR OSHA.
Effects of Overexposure:CNS
    DEPRESSION:DIZZINESS,DROWSINESS,LIGHT-HEADEDNESS,TENDANCY TO
    FALL,IRRITABILITY,APPREHENSION,WEAKNESS,GENERALIZED
    PAIN,HEADACHE,FLUSHING,PERSPIRING,HYPERSALIVATION,LOSS OF
    APPETITE,MOOD CHANGES,VIS UAL EFFECTS,HALUCINATIONS.
Medical Cond Aggravated by Exposure:PERSONS WITH PRE-EXISTING KIDNEY OR
    LIVER AILMENTS MAY BE AT INCREASED RISK FROM EXPOSURE.

=======================  First Aid Measures  =======================

First Aid:SKIN:WASH WITH SOAP AND WATER.EYES:FLUSH WITH WATER FOR 15
    MINUTES.INHAL:REMOVE TO FRESH AIR.TREAT AS IF INGESTED.INGEST:GET
    PROMPT QUALIFIED MEDICAL ATTENTION.USE SUPPORTIVE MEASURES;USE
    IMMEDIATE GA STRIC LAVAGE;GIVE INTRAVENOUS FLUIDS;MAINTAIN AIRWAY.

=====================  Fire Fighting Measures  =====================

Flash Point:NONE
Extinguishing Media:WATER SPRAY,DRY CHEMICAL,CARBON DIOXIDE,FOAM.AS
    APPROPRIATE FOR SURROUNDING FIRE.
Fire Fighting Procedures:USE A SELF-CONTAINED BREATHING APPARATUS AND
    FULL PROTECTIVE EQUIPMENT.COOL FIRE EXPOSED CONTAINERS WITH WATER
    SPRAY.
Unusual Fire/Explosion Hazard:AS WITH ANY DUST THERE IS AN EXPLOSION
    HAZARD.BOND CONTAINERS WHEN TRANSFERRING MATERIALS.

==================  Accidental Release Measures  ==================

Spill Release Procedures:TRANSFER TO A PROPERLY LABELED CONTAINER.
Neutralizing Agent:NONE

======================	Handling and Storage  ======================

Handling and Storage Precautions:HANDLE THIS SUBSTANCE IN THE MANNER
    PRESCRIBED BY SCHEDULE IV OF THE CONTROLLED SUBSTANCES ACT.
Other Precautions:NONE

=============  Exposure Controls/Personal Protection  =============

Respiratory Protection:WHERE ENVIRONMENTAL CONTROLS ARE LACKING OR IN
    ENCLOSED SPACES USE A NIOSH RESPIRATOR FOR DUST.
Ventilation:LOCAL VENTILATION AT THE WORKSITE;MECHANICAL(GENERAL)
    VENTILATION TO MAINTAIN TLV/PEL.
Protective Gloves:IF NEEDED
Eye Protection:SAFETY GLASSES
Other Protective Equipment:LAB COAT.PROVIDE A LOCAL EYE WASH STATION.
Work Hygienic Practices:FOLLOW RECOMMENDATIONS AS SET FORTH IN SCHEDULE
    IV OF THE CONTROLLED SUBSTANCES ACT.
Supplemental Safety and Health
NDC#0140-0066-27.

==================  Physical/Chemical Properties  ==================

HCC:T4
Melt/Freeze Pt:M.P/F.P Text:406F DECOMP
Decomp Temp:Decomp Text:406F,208C
Solubility in Water:APPRECIABLE
Appearance and Odor:CAPSULES;OFF-WHITE TO YELLOW;ODORLESS TO SLIGHT
    ODOR

=================  Stability and Reactivity Data  =================

Stability Indicator/Materials to Avoid:YES
ACIDS(<3)ES(>7).
Stability Condition to Avoid:LIGHT
Hazardous Decomposition Products:IN SOLUTION WITH ACIDS AND BASES,THIS
    ITEM UNDERGOES HYDROLYSIS TO BENZOPHENONE.

====================  Disposal Considerations  ====================

Waste Disposal Methods:DESTROY THIS MATERIAL IN A MANNER PRESCRIBED BY
    SCHEDULE IV OF THE CONTROLLED SUBSTANCES ACT.

 ======================================================================
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