GLAXO INC -- RANITIDINE HYDROCHLORIDE -- 6850-00F039324
===================== Product Identification =====================
Product ID:RANITIDINE HYDROCHLORIDE
MSDS Date:10/01/1988
FSC:6850
NIIN:00F039324
MSDS Number: BWWTF
=== Responsible Party ===
Company Name:GLAXO INC
Address:5 MOORE DR
City:RESEARCH TRIANGLE PARK
State:NC
ZIP:27709-5000
Country:US
Info Phone Num:919-248-2100/2354
Emergency Phone Num:919-248-2100/2700
CAGE:34006
=== Contractor Identification ===
Company Name:GLAXO WELLCOME INC.
Address:5 MOORE DR
Box:13398
City:DURHAM
State:NC
ZIP:27709
Country:US
Phone:919-248-2100
CAGE:34006
============= Composition/Information on Ingredients =============
Ingred Name:RANITIDINE HYDROCHLORIDE *95-1*
CAS:70956-04-6
RTECS #:KM6557000
Fraction by Wt: 100%
OSHA PEL:0.05 MG/M3
===================== Hazards Identification =====================
Routes of Entry: Inhalation:NO Skin:NO Ingestion:NO
Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO
Health Hazards Acute and Chronic:SKIN: IRRITATION, SENSITIZATION.
INHALATION: IRRITATION OF THE MUCOUS MEMBRANES. EYES: IRRITATION.
INGESTION: ADVERSE EFFECTS THAT HAVE BEEN OBSERVED W/RAINITIDINE
USED CLINICALLY ARE REVERSIBLE INFLA MMATION OF THE LIVER WHICH MAY
BE ACCOMPANIED BY JAUNDICE.
Explanation of Carcinogenicity:NONE
Effects of Overexposure:IRRITATION, RASH, SHORTNESS OF BREATH,
WHEEZING, ITCHY RASH, NASAL CONGESTION, RUNNY NOSE, HEADACHE,
JAUNDICE.
======================= First Aid Measures =======================
First Aid:EYES: FLUSH W/LARGE AMOUNTS OF WATER. SKIN: WASH W/SOAP &
WATER. INHALATION: REMOVE TO FRESH AIR. GIVE OXYGEN/CPR IF NEEDED.
INGESTION: RINSE MOUTH, GIVE LARGE QUANTITIES OF WATER & ENCOURAGE
VOMITING . OBTAIN MEDICAL ATTENTION IN ALL CASES.
===================== Fire Fighting Measures =====================
Extinguishing Media:WATER SPRAY, FOAM, MULTI-PURPOSE DRY CHEMICAL
Fire Fighting Procedures:WEAR FULL PROTECTIVE CLOTHING & USE A SELF
CONTAINED BREATHING APPARATUS.
Unusual Fire/Explosion Hazard:AS W/ANY ORGANIC DUST, THERE IS POTENTIAL
FOR EXPLOSION WHEN SUSPENDED IN AIR IN HIGH CONCENTRATIONS.
================== Accidental Release Measures ==================
Spill Release Procedures:WEAR FULL PROTECTIVE EQUIPMENT. COLLECT BY
CAREFULLY SWEEPING/VACUUMING W/HEPA FILTERED VACUUM & PLACE IN
LABELED, SEALED CONTAINER FOR REUSE/DISPOSAL. WASH AREA W/WATER
AFTER VACUUMING.
====================== Handling and Storage ======================
Handling and Storage Precautions:USE PRACTICES THAT WILL MINIMIZE
GENERATION OF DUST.
Other Precautions:AVOID BODY CONTACT.
============= Exposure Controls/Personal Protection =============
Respiratory Protection:RECOMMENDED BY NIOSH/MSHA.
Ventilation:LOCAL EXHAUST VENTILATION
Protective Gloves:REQUIRED
Eye Protection:REQUIRED
Work Hygienic Practices:REMOVE/LAUNDER CONTAMINATED CLOTHING BEFORE
REUSE.
Supplemental Safety and Health
================== Physical/Chemical Properties ==================
Melt/Freeze Pt:M.P/F.P Text:272F
Solubility in Water:COMPLETE
Appearance and Odor:OFF-WHITE TO PALE YELLOW COLORED POWDER
W/CHARACTERISTIC SULFUR-LIKE ODOR
================= Stability and Reactivity Data =================
Stability Indicator/Materials to Avoid:YES
Stability Condition to Avoid:EXTREME HEAT, TEMP >300F.
Hazardous Decomposition Products:TOXIC/CORROSIVE VAPORS, CHLORIDES,
OXIDES OF NITROGEN & SULFUR
==================== Disposal Considerations ====================
Waste Disposal Methods:INCINERATE AT AN APPROVED FACILITY IAW/FEDERAL,
STATE & LOCAL REGULATIONS.
Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.