Toxicity data
Risk phrases
Safety phrases
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This information was last updated on February 25, 2005.
We have tried to make it as accurate and useful as possible, but
can take no responsibility for its use, misuse, or accuracy. We
have not verified this information, and cannot guarantee that it
is up-to-date. General
Synonyms: bromochlorotrifluoroethane, 1-bromo-1-chloro-2,2,2-trifluoroethane,
chalothane, fluorotane, fluothane, anestan, halotan, halothane, halsan,
halotane, narcotan, halan, rhodialothan, Freon 123b1, narcotane, various
further names
Use: inhalation anaesthetic
Molecular formula: C2HBrClF3
CAS No: 151-67-7
EINECS No: 205-796-5
Physical data
Appearance: colourless liquid
Melting point:
Boiling point: 50 C
Vapour density: 6.8 (calculated, air=1)
Vapour pressure: 232 mm Hg at 20C
Density (g cm-3): 1.872
Flash point:
Explosion limits:
Autoignition temperature:
Water solubility: slight
Stability
Stable, but may be light sensitive. Incompatible with
rubber, plastics, strong oxidizing agents. Tarnishes most metals. Non-combustible.
May be stabilized with 0.01%
thymol.
Toxicology
Severe eye irritant. May act as a carcinogen or
mutagen. May cause reproductive damage. Experimental teratogen.
Harmful if inhaled.
May be harmful in contact with the skin or if swallowed. Narcotic.
Ceiling limit 2 ppm.
(The meaning of any toxicological abbreviations which
appear in this section is given
here.)
ORL-HMN LDLO 140 mg kg-1
IHL-HMN LCLO 7000 ppm/3h
IVN-MAN LDLO 129 mg kg-1
ORL-RAT LD50 5680 mg kg-1
IHL-RAT LC50 29000 ppm
IHL-MUS LC50 98 g/m3/2h
ORL-GPG LD50 6000 mg kg-1
(The meaning of any risk phrases which appear in this section is
given
here.)
R20 R36 R40 R61.
Transport information
(The meaning of any UN hazard codes which appear in this section
is given
here.)
Aviation regulated liquid. UN No 3334. Major hazard class 9.0.
Personal protection
Safety glasses, good ventilation.
(The meaning of any safety phrases which appear in this section
is given here.)
S23 S26 S36 S37 S45 S53.