Synonyms: l-(-)-beta-(3,4-dihydroxyphenyl)-alpha-methylalanine, methyldopa, aldomet, AMD, Bayer 1440 L, baypresol, dopamet, dopatec, dopegyt, l-(alpha-md), (-)-methyldopa, l-methyldopa, aldometial, aldomin, alpha medopa, hyperpax, modomet, medopren, presolisin, sedometril, sembrina, aldomine, numerous other systematic and non-systematic names
Use: antihypertensive
Molecular formula: C₁₀H₁₃NO₄. 1.5H₂O
CAS No: 41372-08-1
EINECS No:

Physical data

Appearance: colourless to white crystalline powder
Melting point: ca. 300 C (decomposes)
Boiling point:
Vapour density:
Vapour pressure:
Density (g cm^-3):
Flash point:
Explosion limits:
Autoignition temperature:
Water solubility: moderate

Stability

Very hygroscopic. Undergoes catalytic oxygenation in the presence of magnesium, cupric, cobalt, nickel and ferric ions. Store under a dry atmosphere.

Toxicology

May cause reproductive damage. Experimental carcinogen and teratogen. May be harmful if swallowed or inhaled.

Toxicity data
(The meaning of any abbreviations which appear in this section is given here.)
ORL-RAT LD50 5000 mg kg^-1
IPR-MUS LD50 150 mg kg^-1
IVN-MUS LD50 1700 mg kg^-1
ORL-WMN TDLO 900 mg kg^-1 /13w-i

Risk phrases
(The meaning of any risk phrases which appear in this section is given here.)

Transport information

(The meaning of any UN hazard codes which appear in this section is given here.)

Personal protection

Safety glasses, adequate ventilation.

Safety phrases
(The meaning of any safety phrases which appear in this section is given here.)

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This information was last updated on November 10, 2003. We have tried to make it as accurate and useful as possible, but can take no responsibility for its use, misuse, or accuracy. We have not verified this information, and cannot guarantee that it is up-to-date.