Fluorescein disodium salt dihydrate

MSDS Language: EN
Country:
                      **** MATERIAL SAFETY DATA SHEET ****

  Fluorescein
90367

        **** SECTION 1 - CHEMICAL PRODUCT AND COMPANY IDENTIFICATION ****

MSDS Name: Fluorescein
Catalog Numbers:
     F/1200
Synonyms:
     9-(o-Carboxyphenyl)-6-hydroxy-3-isoxanthenone; Dihydroxyfluorane;
     3,6-Fluorandiol.
Company Identification:  Fisher Scientific UK
                         Bishop Meadow Road
                         Loughborough, Leicestershire
                         LE11 5RG, UK
For information, call:   01509 231166
For emergencies, call:   01509 231166

          **** SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS ****

+----------------+--------------------------------------+----------+-----------+-----------+---------------+
|      CAS#      |              Chemical Name           |    %     |  EINECS#  |Haz Symbols| Risk Phrases  |
|----------------|--------------------------------------|----------|-----------|-----------|---------------+
|     2321-07-5  |Fluorescein                           |  100 %   | 219-031-8 |||
+----------------+--------------------------------------+----------+-----------+-----------+---------------+
          Hazard Symbols: XI
          Risk Phrases: 36

                  **** SECTION 3 - HAZARDS IDENTIFICATION ****

                               EMERGENCY OVERVIEW
Irritating to eyes.The toxicological properties of this material
have not been fully investigated.

Potential Health Effects
     Eye:
          Causes eye irritation.  May cause chemical conjunctivitis.
     Skin:
          May cause skin irritation.
     Ingestion:
          May cause gastrointestinal irritation with nausea, vomiting and
          diarrhea. The toxicological properties of this substance have not
          been fully investigated.
     Inhalation:
          May cause respiratory tract irritation. The toxicological properties
          of this substance have not been fully investigated.
     Chronic:
          No information found.

                    **** SECTION 4 - FIRST AID MEASURES ****

     Eyes:
          Flush eyes with plenty of water for at least 15 minutes,
          occasionally lifting the upper and lower eyelids. Get medical aid.
     Skin:
          Flush skin with plenty of water for at least 15 minutes while
          removing contaminated clothing and shoes. Get medical aid if
          irritation develops or persists.
     Ingestion:
          If victim is conscious and alert, give 2-4 cupfuls of milk or water.
          Never give anything by mouth to an unconscious person. Get medical
          aid.
     Inhalation:
          Remove from exposure and move to fresh air immediately. If not
          breathing, give artificial respiration. If breathing is difficult,
          give oxygen. Get medical aid.
     Notes to Physician:

                  **** SECTION 5 - FIRE FIGHTING MEASURES ****

     General Information:
          As in any fire, wear a self-contained breathing apparatus in
          pressure-demand, MSHA/NIOSH (approved or equivalent), and full
          protective gear. During a fire, irritating and highly toxic gases
          may be generated by thermal decomposition or combustion.
     Extinguishing Media:
          In case of fire, use water, dry chemical, chemical foam, or
          alcohol-resistant foam.

                **** SECTION 6 - ACCIDENTAL RELEASE MEASURES ****

     General Information: Use proper personal protective equipment as indicated
                          in Section 8.
     Spills/Leaks:
          Vacuum or sweep up material and place into a suitable disposal
          container. Reduce airborne dust and prevent scattering by moistening
          with water. Clean up spills immediately, observing precautions in
          the Protective Equipment section.

                   **** SECTION 7 - HANDLING and STORAGE ****

     Handling:
          Wash thoroughly after handling. Wash hands before eating. Remove
          contaminated clothing and wash before reuse. Use with adequate
          ventilation. Avoid contact with eyes, skin, and clothing. Avoid
          ingestion and inhalation.
     Storage:
          Store in a cool, dry place. Keep container closed when not in use.

          **** SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION ****

     Engineering Controls:
          Facilities storing or utilizing this material should be equipped
          with an eyewash facility and a safety shower. Use adequate general or
          local exhaust ventilation to keep airborne concentrations below the
          permissible exposure limits.
     Personal Protective Equipment

                 Eyes:
                       Wear appropriate protective eyeglasses or chemical
                       safety goggles as described by OSHA's eye and face
                       protection regulations in 29 CFR 1910.133 or European
                       Standard EN166.
                 Skin:
                       Wear appropriate protective gloves to prevent skin
                       exposure.
             Clothing:
                       Wear appropriate protective clothing to prevent skin
                       exposure.
          Respirators:
                       Follow the OSHA respirator regulations found in 29
                       CFR 1910.134 or European Standard EN 149. Always use
                       a NIOSH or European Standard EN 149 approved
                       respirator when necessary.

             **** SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES ****

Physical State:             Solid
Color:                      red-orange
Odor:                       None reported.
pH:                         Not available.
Vapor Pressure:             Not available.
Viscosity:                  Not available.
Boiling Point:              Not available.
Freezing/Melting Point:     290 deg C
Autoignition Temperature:   Not applicable.
Flash Point:                Not applicable.
Explosion Limits, lower:    Not available.
Explosion Limits, upper:    Not available.
Decomposition Temperature:  Not available.
Solubility in water:        Insoluble in water.
Specific Gravity/Density:   Not available.
Molecular Formula:          C20H12O5
Molecular Weight:           332.081

                 **** SECTION 10 - STABILITY AND REACTIVITY ****

     Chemical Stability:
          Stable under normal temperatures and pressures.
     Conditions to Avoid:
          Incompatible materials, dust generation.
     Incompatibilities with Other Materials:
          Strong oxidizing agents.
     Hazardous Decomposition Products:
          Carbon monoxide, carbon dioxide.
     Hazardous Polymerization: Has not been reported.

                **** SECTION 11 - TOXICOLOGICAL INFORMATION ****

     RTECS#:
          CAS# 2321-07-5: LM5075000
     LD50/LC50:
          CAS# 2321-07-5: Draize test, rabbit, eye: 100 uL/24H Severe.
     Carcinogenicity:
       Fluorescein -
          Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA.
          See actual entry in RTECS for complete information.

                  **** SECTION 12 - ECOLOGICAL INFORMATION ****



                 **** SECTION 13 - DISPOSAL CONSIDERATIONS ****

Products which are considered hazardous for supply are classified as Special
Waste and the disposal of such chemicals is covered by regulations which may
vary according to location.  Contact a specialist disposal company or the local
waste regulator for advice.  Empty containers must be decontaminated before
returning for recycling.

                  **** SECTION 14 - TRANSPORT INFORMATION ****

     IATA
          Not regulated as a hazardous material.
     IMO
          Not regulated as a hazardous material.
     RID/ADR
          Not regulated as a hazardous material.

                  **** SECTION 15 - REGULATORY INFORMATION ****

 European/International Regulations
     European Labeling in Accordance with EC Directives
          Hazard Symbols: XI
          Risk Phrases:
                       R 36  Irritating to eyes.
          Safety Phrases:
   WGK (Water Danger/Protection)
          CAS# 2321-07-5: 1
   United Kingdom Occupational Exposure Limits

   United Kingdom Maximum Exposure Limits

   Canada
          CAS# 2321-07-5 is listed on Canada's DSL List.
          CAS# 2321-07-5 is not listed on Canada's Ingredient Disclosure List.
   Exposure Limits
 US FEDERAL
     TSCA
          CAS# 2321-07-5 is listed on the TSCA inventory.

                  **** SECTION 16 - ADDITIONAL INFORMATION ****

     MSDS Creation Date:  6/23/2004  Revision #0 Date: Original.

     The information above is believed to be accurate and represents the best
     information currently available to us. However, we make no warranty of
     merchantability or any other warranty, express or implied, with respect to
     such information, and we assume no liability resulting from its use. Users
     should make their own investigations to determine the suitability of the
     information for their particular purposes. In no way shall the company be
     liable for any claims, losses, or damages of any third party or for lost
     profits or any special, indirect, incidental, consequential or exemplary
     damages, howsoever arising, even if the company has been advised of
     the possibility of such damages.
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